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Glossary Alanine Aminotransferase

enzyme indicating liver health, also known as ALT

Alanine Aminotransferase (ALT), also known as Serum Glutamate Pyruvate Transaminase (SGPT), is an enzyme primarily found in the liver. It plays a crucial role in converting alanine, an amino acid, into pyruvate, which is essential for energy production. Elevated levels of ALT in the blood can indicate liver damage or disease, making it a valuable marker in diagnosing liver conditions.

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research Variations in alanine aminotransferase levels within the normal range predict metabolic and androgenic phenotypes in women of reproductive age

8 citations , October 2010 in “Scandinavian Journal of Clinical & Laboratory Investigation”

This study found that normal ALT levels in women of reproductive age are linked with metabolic and androgenic abnormalities, suggesting ALT could be used beyond liver disease diagnoses.

research Single nucleotide polymorphisms associated with elevated alanine aminotransferase in patients receiving asunaprevir plus daclatasvir combination therapy for chronic hepatitis C

2 citations , July 2019 in “PLOS ONE”

This study found that the CYP3A4 rs4646437 genotype was significantly associated with ALT elevation in Japanese patients undergoing asunaprevir plus daclatasvir therapy for chronic HCV infection, suggesting genotyping may help in monitoring patients safely.

research The retarded hair growth ( rhg ) mutation in mice is an allele of ornithine aminotransferase ( Oat )

9 citations , January 2014 in “Molecular Genetics and Metabolism Reports”

This study discovered that a specific G to C mutation in the ornithine aminotransferase gene is linked to the retarded hair growth phenotype in mice and may serve as a model for human gyrate atrophy.

research Pooled safety and tolerability data from four placebo-controlled teriflunomide studies and extensions

72 citations , November 2015 in “Multiple Sclerosis and Related Disorders”

This study concluded that teriflunomide has a consistent and manageable safety profile, with common mild-to-moderate adverse events and no new safety concerns identified over up to 12 years of treatment.

research Clinical and hepatic evaluation in adult dengue patients: a prospective two-month cohort study

53 citations , December 2012 in “Revista da Sociedade Brasileira de Medicina Tropical”

In this study, liver transaminase levels and various symptoms persisted in some adult dengue patients even two months after diagnosis.

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community concerns about starting minoxidil

1 upvotes 5 years ago

An 18-year-old woman experiencing hair loss due to stress, possible PCOS, and low vitamin D is concerned about starting 5% minoxidil foam, prescribed by her doctor, due to potential facial hair growth. She is also using a topical steroid for scalp sensitivity and pain.

community Testosterone, gray hair, low vitamin D, and switching to oral Minoxidil

5 upvotes 5 years ago

A woman experiencing hair loss due to high testosterone and low vitamin D is using treatments like Dutasteride, Rogaine, zinc, ketoconazole shampoo, dermastamp, iRestore, multivitamins, scalp massager, and vitamin D. She plans to switch to oral Minoxidil under medical supervision.

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