research Applications and Limitations of Lipid Nanoparticles in Dermal and Transdermal Drug Delivery via the Follicular Route
Lipid nanoparticles can help deliver drugs through hair follicles but struggle to penetrate deeper skin layers.
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research Non-Viral Delivery of the CRISPR/Cas System: DNA Versus RNA Versus RNP
RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.
research Vitamin D Status Assessment: Lack of Correlation Between Serum and Hair 25-Hydroxycholecalciferol Levels in Healthy Young Adults
Vitamin D levels in hair don't match those in blood, so hair isn't a reliable indicator of Vitamin D status.
research A Phase I, Open-Label, Sequential, Single-Dose Clinical Trial to Evaluate the Pharmacokinetics, Pharmacodynamics, and Safety of IVL3001, a Finasteride-Based Novel Long-Acting Injection for Androgenetic Alopecia
IVL3001 is safe, effective, and better than oral finasteride for treating hair loss.
research Biochemical Evidence That Small Proline-Rich Proteins and Trichohyalin Function in Epithelia by Modulation of the Biomechanical Properties of Their Cornified Cell Envelopes
Small proline-rich proteins and trichohyalin help make epithelial tissues tougher and more flexible.
research Poly (ɛ-Caprolactone)–Chitosan–Poly (Vinyl Alcohol) Nanofibrous Scaffolds for Skin Excisional and Burn Wounds in a Canine Model
The scaffolds significantly sped up wound healing in dogs and were safe.
research Physicochemical Characterization of Finasteride Nanosystem for Enhanced Topical Delivery
Chitosan-decorated finasteride nanosystems improve skin retention and could be a better treatment for hair loss.
research Nanomaterials in Hair Care and Treatment
Nanomaterials can improve hair care products and treatments, including hair loss and alopecia, by enhancing stability and safety, and allowing controlled release of compounds, but their safety in cosmetics needs more understanding.
research Cryopreservation of Hair-Follicle Associated Pluripotent Stem Cells Maintains Differentiation and Hair-Growth Potential
Freezing and storing special stem cells from hair follicles keeps their ability to grow hair and turn into different cell types.
research Expression and Tissue Distribution Analysis of Angiotensin II in Sheep Skins Associated with White and Black Coat Colors
Angiotensin II is found at higher levels in black sheep skin and may influence coat color.
research Prevalence Of Cobalt In The Environment And Its Role In Biological Processes
Cobalt is important for health but too much or too little can cause health problems, and its environmental buildup is a concern.
research Clinical and Dermatoscopic Features of Temporal Triangular Alopecia in Infants
Temporal triangular alopecia in infants is mostly seen in males at birth, with unique features that help with diagnosis.
research A New Mechanism for Resonance Rayleigh Scattering Detection of Minoxidil Based on Catalytic Oxidation of Silver Nanoparticles
A new, quick method detects minoxidil using silver nanoparticles.
research Nitric Oxide Synergizes Minoxidil Delivered by Transdermal Hyaluronic Acid Liposomes for Multimodal Androgenetic Alopecia Therapy
The new hair loss treatment combining nitric oxide and minoxidil in a special carrier is effective for hair regrowth.
research Hair Follicle Epidermal Stem Cells Define a Niche for Tactile Sensation
Skin stem cells in hair follicles are important for touch sensation.
research Short-Term Cryoprotectant-Free Cryopreservation at −20°C Does Not Affect the Viability and Regenerative Capacity of Nanofat
Storing nanofat at -20°C for 7 days does not harm its ability to regenerate.
research Extemporaneous Topical Minoxidil Solutions for the Treatment of Androgenetic Alopecia: Stability Studies and Incorporation Tests of Active Pharmaceutical Ingredients in Aloplus Total Base
The new minoxidil lotion using Aloplus Total is stable and can be mixed with other ingredients for treating hair loss.
research Matrix Effects And Application Of Matrix Effect Factor
Matrix effects in LC-MS can be managed but not completely avoided.
research The Use of Keratin Biomaterials Derived from Human Hair for the Promotion of Rapid Regeneration of Peripheral Nerves
Keratin from human hair helps nerves heal faster.
research An Autophagy-Related Kinase Is Essential for the Symbiotic Relationship Between Phaseolus Vulgaris and Both Rhizobia and Arbuscular Mycorrhizal Fungi
A specific enzyme is crucial for the bean plant's relationship with certain beneficial soil bacteria and fungi.
research Effect of P144 (Anti-TGF-β) in an In Vivo Human Hypertrophic Scar Model in Nude Mice
P144® improves hypertrophic scars by reducing size and thickness and increasing elasticity.
research Lidocaine-Loaded Solid Lipid Microparticles Produced from Gas-Saturated Solutions for Wound Applications
Lidocaine-loaded microparticles effectively relieve pain and fight bacteria in wounds.
research Binding Interactions of Keratin-Based Hair Fiber Extract to Gold, Keratin, and BMP-2
Keratin from hair binds well to gold and BMP-2, useful for bone repair.
research New and Consolidated Therapeutic Options for Pubertal Induction in Hypogonadism: In-Depth Review of the Literature
There are various effective hormone treatments for puberty induction in boys and girls with hypogonadism, and starting treatment early is important.
research The Study on Biological Function of Keratin 26, a Novel Member of Liaoning Cashmere Goat Keratin Gene Family
Keratin 26 affects cashmere goat hair growth and is influenced by various treatments.
research PEO-b-PCL Grafted Niosomes: The Cooperativity of Amphiphilic Components and Their Properties In Vitro and In Vivo
The new drug delivery systems made with surfactants and block polymers are stable and not toxic.
research Epidermal Structure Created by Canine Hair Follicle Keratinocytes Enriched with Bulge Cells in a Three-Dimensional Skin Equivalent Model In Vitro: Implications for Regenerative Therapy of Canine Epidermis
Keratinocytes from dog hair follicles can create a functional skin layer in a lab model, useful for dog skin therapy.
research Exploring the Impact of the Microbiome on Neuroactive Steroid Levels in Germ-Free Animals
Gut microbes significantly affect brain steroid levels.
research SCD1 Sustains Homeostasis of Bulge Niche via Maintaining Hemidesmosomes in Basal Keratinocytes
SCD1 is important for hair growth by keeping the connection in skin cells where hair stem cells live stable.
research The Connection of 5-Alpha Reductase Inhibitors to the Development of Depression
5-alpha reductase inhibitors, like finasteride and dutasteride, may cause depression, but more research is needed to understand why.