31 citations
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April 2010 in “British journal of dermatology/British journal of dermatology, Supplement” This report describes two patients with frontal fibrosing alopecia who developed acute hair loss on their limbs, revealing that the limb alopecia had similar histological features to scalp alopecia.
7 citations
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August 2019 in “American Journal of Dermatopathology” This study found that limb hair loss in frontal fibrosing alopecia is inflammatory and permanent, but lacks the classic scarring features seen in scalp alopecia, prompting potential misdiagnosis as alopecia areata.
2 citations
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February 2020 in “Chinese Medical Journal” This case report highlights the missed diagnosis of systemic lupus erythematosus in a pregnant woman, leading to her death despite treatment efforts after cesarean section and epidural anesthesia complications.
December 2024 in “African Journal of Biomedical Research” This study reported that the combined use of dexmedetomidine and ketamine, along with peripheral nerve blocks, provided adequate sedation and analgesia with maintained hemodynamic stability in patients undergoing minor surgical procedures like split skin grafting.
This study suggests that a portable OCT system may be useful for the clinical diagnosis and evaluation of skin diseases and laser treatment outcomes.
March 2011 in “Journal of clinical and experimental investigations” This study describes two thallium poisoning outbreaks, highlighting characteristic symptoms like hair loss and peripheral neuropathy, and emphasizes that such poisoning can stem from accidental or criminal ingestion.
39 citations
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April 2023 in “Science Advances” This study identified that bone marrow-derived CD34+ cells act as fibroblast progenitors to enhance tissue regeneration in ischemic limbs by promoting angiogenesis through interactions with macrophages.
1 citations
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November 2017 This chapter reviews classic regeneration models in planarian worms and amphibian limbs, focusing on the role of stem cells, and reports no new experimental results.
1 citations
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April 2015 in “Neurology” This study found that hyperpigmented skin changes resembling Schamberg’s purpura occur in areas affected by CRPS and can also appear on mirror-image locations of unaffected limbs, potentially improving with the condition's treatment.
27 citations
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January 2012 in “Current Topics in Microbiology and Immunology” This study found similarities in the regeneration processes of MRL mouse ears and axolotl limbs, involving G2 cell cycle arrest and nerve-dependent mitosis, but the role of p21 in axolotl limb regeneration remains uncertain.
3 citations
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August 2017 in “Clinical case reports” A rare skin condition causes red and dark patches on the face and limbs.
July 2025 in “International Journal of Trichology” This case study reported on a 6-year-old boy with frictional alopecia in the lower limbs, likely linked to his habit of cross-legged sitting and occasional rubbing, highlighting the condition's rarity in pediatric cases and emphasizing the need for further research in this age group.
18 citations
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January 1997 in “British Journal of Dermatology” In this study, five women with androgenetic alopecia developed severe hypertrichosis on the face and limbs after using 5% topical minoxidil, which resolved after discontinuing the treatment.
4 citations
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December 2023 in “Clinical Cosmetic and Investigational Dermatology” This study found that in people with leprosy sequelae, ulcers on the lower limbs exhibited decreased microbial diversity and reduced abundance of specific bacteria compared to normal skin, with skin metabolites closely linked to these microbial changes.
1 citations
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July 2024 in “Nanomedicine” This study demonstrated that EVs from pluripotent stem cell-derived mesenchymal stem cells improved recovery and function in ischemic lower limbs by enhancing angiogenesis through the ERK/MAPK signaling pathway.
1 citations
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March 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” This study used confocal Brillouin microscopy to observe that a decrease in tissue compressibility occurs during the development and regeneration of axolotl limbs, suggesting mechanical changes linked to regeneration stages undetectable by fluorescence microscopy.
January 2022 in “IAR Journal of Parasitology & Infectious Disease” This study observed that 30.1% of older adults had nail changes, predominantly affecting the lower limbs, and hair disorders were less common, with alopecia being the only type recorded.
88 citations
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December 2003 in “Journal of Biological Chemistry” This study identified epiprofin as a highly tissue-specific nuclear protein that promotes cell proliferation, mainly expressed in the developing teeth, hair follicles, and limbs of embryonic mice.
32 citations
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February 2008 in “Developmental dynamics” This study indicates that the Sp6 gene is crucial for the development of skin, teeth, limbs, and lungs in mice, possibly through regulating apoptosis.
21 citations
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November 1980 in “PubMed” This study describes a newly identified mite species, Demodex zalophi, found on captive sea lions and highlights its unique traits, including being the first of its kind described in marine mammals.
February 2026 in “JEADV Clinical Practice” This report describes a rare case of scarring alopecia, diagnosed as lichen planopilaris (LPP), affecting solely the limbs, highlighting the necessity for thorough evaluation of LPP beyond the scalp.
January 2026 in “JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH” In this case study, a 62-year-old male with a history of uncontrolled diabetes and chronic kidney disease was diagnosed with perforating folliculitis after presenting with dark, raised, pruritic lesions on his limbs, confirmed by histopathological examination showing collagen extruding into hair follicles.
January 2026 in “Acta Dermato Venereologica” This source reports that four weeks of dupilumab treatment led to notable improvement in skin lesions, including multiple erythematous patches and papules on the face, back, and limbs.
June 2025 in “Reports of Vinnytsia National Medical University” In this study, young Ukrainian men with alopecia areata were found to generally have higher body circumference measurements, particularly in the upper limbs, lower limbs, and trunk, compared to healthy controls, suggesting potential markers for the disease and aiding personalized diagnosis and treatment approaches.
December 2024 in “Reports of Vinnytsia National Medical University” In this study, young Ukrainian men with alopecia areata were found to have a "subpathological" body type, characterized by shorter lower limbs and longer upper limbs and torso compared to healthy peers.
May 2024 in “Journal of ayurveda and integrated medical sciences” In this study, a clinical trial on a vegan patient with Vitamin B12 deficiency showed that administering Amra Beej Majja Churna over two months increased serum Vitamin B12 levels and alleviated symptoms like hair loss and tingling sensations in the lower limbs.
44 citations
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January 1997 in “British Journal of Dermatology” In this study, five women with androgenetic alopecia experienced severe facial and limb hypertrichosis after using 5% topical minoxidil, which resolved after discontinuing the treatment.
11 citations
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January 2009 in “Indian journal of dermatology, venereology, and leprology” This review discusses the characteristics, geography, and treatment challenges of dermatitis cruris pustulosa et atrophicans in men, emphasizing the need for further research on its etiology and management; it presents no new clinical findings.
1 citations
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September 2017 in “BMJ” The man has a disease causing skin patches, thickened nerves, and mild muscle weakness.
18 citations
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March 1992 in “Archives of Dermatology” This case report presents a 28-year-old man with scarring alopecia unresponsive to topical treatments, alongside a family history of keratosis pilaris and unique curly scalp hair.