109 citations
,
April 2000 in “European Urology” In this study, significantly fewer men treated with finasteride for moderate to severe BPH symptoms experienced acute urinary retention or required subsequent BPH-related surgery compared to placebo-treated patients.
January 2020 in “Journal of Men s Health” In this study of BPH patients with testosterone deficiency, the combination of TU and dutasteride reduced prostate volume and improved testosterone-related symptoms but was less effective for sexual function compared to TU alone, indicating caution in using dutasteride for those with sexual dysfunction concerns.
This study developed and validated three analytical techniques for the simultaneous quantification of Finasteride and Tamsulosin Hydrochloride in pharmaceutical dosage forms, with proven accuracy and precision.
9 citations
,
February 2018 in “Journal of Pharmaceutical and Biomedical Analysis” This study validated a highly selective and fast LC–MS/MS method for accurately measuring levels of tadalafil and finasteride in human plasma, adhering to international bioanalytical guidelines.
June 2026 in “British Journal of Dermatology” This study reviewed human evidence on the effects of 5α-reductase inhibitors, finasteride and dutasteride, on semen parameters and gonadotrophins, finding finasteride causes mild, reversible changes, while dutasteride may lead to more pronounced and potentially less reversible impacts, suggesting caution for those planning to conceive.
March 2005 in “Current Prostate Reports”
March 2014 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Dutasteride 0.5mg was found to be more effective than finasteride 1mg in treating male pattern hair loss, with similar side effects.
January 2013 in “Zhonghua linchuang yishi zazhi” This study found that finasteride administration for more than one month before TURP surgery significantly reduces blood loss in patients with benign prostatic hyperplasia.
7 citations
,
March 2015 in “The American Journal of the Medical Sciences” This study found that finasteride reduced VEGF expression and microvessel density in the renal tissue of diabetic rats, suggesting its potential for treating diabetic microvascular complications.
January 2012 in “Земский врач” This article reviews research on the treatment of benign prostatic hyperplasia and suggests that 5-alpha-reductase inhibitors like finasteride may improve therapeutic outcomes, without providing new clinical results.
7 citations
,
September 2014 in “Mass spectrometry letters” This study reported that a liquid-liquid extraction method using methyl tert-butyl ether and methylene chloride was most effective for extracting dutasteride and its internal standard from rat plasma.
2 citations
,
October 2010 in “European Journal of Drug Metabolism and Pharmacokinetics” Researchers developed a quick and sensitive way to measure finasteride in blood using a small sample size.
10 citations
,
May 2010 in “Analytica Chimica Acta” This study reported the development of two highly sensitive ELISA assays to detect banned substances finasteride and dutasteride in human urine, offering better sensitivity than existing HPLC/MS/MS methods.
2 citations
,
May 2019 in “PubMed” This study on rats found that finasteride and dutasteride increased collagen density in penile tissues and caused changes in prostate cells, but did not significantly alter erectile pressures compared to controls.
December 2010 in “Actas Urológicas Españolas” This abstract outlines a study evaluating dutasteride's effect on perioperative bleeding during transurethral resection of the prostate, but does not report any new clinical results.
97 citations
,
January 2014 in “Journal of The American Academy of Dermatology” This study found that dutasteride increased hair growth and restoration in men with androgenetic alopecia more effectively than finasteride and was well tolerated over 24 weeks.
April 2020 in “Online journal of complementary & alternative medicine” This article discusses the FDA approval of bremelanotide for premenopausal women with hypoactive sexual desire disorder and reports no clinical results.
April 2016 in “Journal of The American Academy of Dermatology” Dutasteride works better than finasteride for hair growth with similar side effects.
February 2014 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” This review discusses a study on the efficacy and safety of different doses of dutasteride compared to placebo and finasteride in treating men with androgenetic alopecia and reports no new results.
92 citations
,
June 2010 in “Journal of The American Academy of Dermatology” This study found that 0.5 mg of dutasteride significantly improved hair growth compared to placebo and was well tolerated over six months in men with male pattern hair loss.
This study found that Finasteride Dispersible Tablets, prepared with an optimized prescription, disintegrate quickly, disperse well, and have a high dissolution speed, suitable for industrial production.
26 citations
,
June 2010 in “Acta Pharmaceutica” The researchers reported that they successfully developed and validated RP-HPLC and TLC methods for accurately measuring tamsulosin hydrochloride and finasteride in combination forms.
June 2018 in “The Journal of Sexual Medicine” This study found no significant difference in semen parameters or reproductive hormone levels between men taking low-dose finasteride for androgenic alopecia and those not on the medication.
38 citations
,
August 2003 in “International Journal of Urology” In this study, androgen deprivation, particularly through finasteride treatment, effectively reduced chronic bacterial prostatitis severity in rats, suggesting potential for improved treatment modalities combining finasteride and levofloxacin.
September 2020 in “Scientific periodicals of Ukraine” This study found that the combination therapy of Flosin and Prostamol Uno over nine years was well tolerated and equally effective in managing benign prostatic hyperplasia symptoms as the combination of doxazosin and finasteride, with fewer adverse events reported.
5 citations
,
November 1994 in “BMJ” Merck will refund the cost of the drug finasteride if it doesn't improve symptoms within six months or if the patient needs surgery within two years.
January 2021 in “Thieme Medical and Scientific Publishers Private Limited eBooks” March 2010 in “European Urology Supplements”
15 citations
,
January 2017 in “Advances in Experimental Medicine and Biology” This review discusses the effects of 5ARI drugs on male reproductive parameters, reporting potential decreases in sperm count and motility more significantly in men with pre-existing oligozoospermia, but does not provide fertility outcomes.
January 2005 in “国外医药:植物药分册” African plum is linked to treating BPH and has economic benefits.