Effect of a Combination of Dutasteride and Parenteral Testosterone Undecanoate on Testosterone Deficiency Symptoms and Prostate in Patients with Testosterone Deficiency and Benign Prostatic Hyperplasia
January 2020
in “
Journal of Men s Health
”
TLDR The combination treatment reduced prostate size and improved testosterone deficiency symptoms but was less effective for sexual function.
The study examined the effects of combining testosterone undecanoate (TU) and dutasteride in 130 patients with testosterone deficiency (TD) and benign prostatic hyperplasia (BPH). It found that both treatments improved testosterone levels and alleviated TD symptoms, but the combination treatment significantly reduced prostate volume more than TU alone. However, the combination was less effective in improving sexual function symptoms. The study concluded that while the combination therapy effectively reduced prostate volume, caution was advised when using dutasteride in patients primarily concerned with sexual dysfunction.
