223 citations,
September 2018 in “Rheumatology” JAK inhibitors are effective in treating various immune-related diseases, not just rheumatoid arthritis.
176 citations,
August 2015 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.
138 citations,
July 2015 in “Clinical, Cosmetic and Investigational Dermatology” Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.
68 citations,
May 2011 in “European Journal of Dermatology” Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.
34 citations,
October 2011 in “Pathology Research International” Behçet's Disease may be caused by genetic and environmental factors leading to abnormal immune responses, and stress management and new treatments could improve patient outcomes.
27 citations,
February 2009 in “Autoimmunity Reviews” The European Society of Cutaneous Lupus Erythematosus created a questionnaire to standardize patient assessment and improve care for cutaneous lupus.
22 citations,
August 1999 in “Experimental Dermatology” Certain drugs can cause early hair growth in mice by affecting the nerves.
20 citations,
June 2010 in “Genes and Immunity” Blood tests can help understand the genetic differences in people with alopecia areata, including how severe it is and if it's inherited.
17 citations,
August 2019 in “JAMA Facial Plastic Surgery” Some men lost hair after deoxycholic acid treatment for neck fat, but most saw improvement or resolution.
69 citations,
May 2009 in “Journal of Investigative Dermatology” Stress might contribute to hair loss in alopecia areata.
4 citations,
January 2011 in “Journal of UOEH” Autoimmune hair loss may be linked to increased Th1 and Th17 cells and decreased Th2 cells.
1 citations,
October 2023 in “Skin research and technology” LC-OCT is an effective new method for diagnosing classic lichen planopilaris.
May 2021 in “International journal of developmental research” Estrogens and progesterone are key in regulating melasma pigmentation.
488 citations,
July 2021 in “Cell” Fibroblasts are crucial for tissue repair and inflammation, and understanding them can help treat fibrotic diseases.
112 citations,
January 2013 in “Experimental dermatology” Faulty Notch signalling may cause hair follicle changes and inflammation in hidradenitis suppurativa.
45 citations,
April 2019 in “International Immunology” The study concluded that immune cells attacking hair follicles cause hair loss in alopecia, with genetics and environment also playing a role, and highlighted the potential of certain treatments.
14 citations,
October 2019 in “International Journal of Women's Health” Menopausal acne is treated with medications and lifestyle changes, but careful choice is needed due to side effects.
9 citations,
March 2022 in “Frontiers in Immunology” Foxp3+ Regulatory T Cells are important for immunity and tolerance, affect hair growth and wound healing, and their dysfunction can contribute to obesity-related diseases and other health issues.
7 citations,
February 2015 in “Journal of comparative pathology” CD8+ T cells play a key role in graft-versus-host disease in certain mice models.
1 citations,
November 2023 in “Life” Hyaluronic acid injections can improve mouth opening and quality of life in scleroderma patients.
13 citations,
January 2018 in “Yonsei Medical Journal” A specific gene mutation causes Olmsted syndrome.
26 citations,
September 2013 in “Journal of Dermatological Science” Serum granulysin levels can indicate the activity and prognosis of alopecia areata.
Hidradenitis Suppurativa has genetic links, with certain gene mutations more common in patients and a third of cases having a family history.
16 citations,
November 2008 in “Journal of the American Academy of Dermatology” Consider necrolytic acral erythema in similar cases and treat with oral zinc sulfate.
11 citations,
October 2021 in “Stem Cell Research & Therapy” Hair follicle stem cells reduced hair loss and inflammation in mice with a condition similar to human alopecia.
February 2024 in “Journal of dermatology” CGF therapy may help hair regrowth and improve scars in DLE patients.
January 2021 in “Our Dermatology Online” A young man's hair loss was the only sign of syphilis, which improved after treatment.
1 citations,
November 2021 in “Biomedicines” Understanding how acne develops in different diseases could lead to new treatments.
3 citations,
September 2021 in “BioEssays” Dandruff might be caused by changes in how hair follicles naturally release oils and an immune response to this imbalance.
September 2024 in “Skin Research and Technology” AFM can help diagnose lichen planopilaris by identifying specific hair structure changes.