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The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Fat cells in the skin help start healing and form important repair cells after injury.

Eating 500 fewer calories a day and making lifestyle changes can improve PCOS symptoms and reduce diabetes risk; more research is needed on its causes and treatments.

Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.

Metformin and rosiglitazone improve blood vessel function in women with PCOS, with metformin also reducing insulin resistance and testosterone levels.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

Metformin has limited effectiveness for improving PCOS symptoms and lacks clear benefits, needing more research to confirm its efficacy.

Quercetin may help with PCOS symptoms, but more research is needed.

Metformin should be used for PCOS mainly in those with glucose intolerance, and has limited benefits for infertility or hirsutism.

Obesity worsens Polycystic Ovary Syndrome symptoms, and weight loss is a key treatment.

Male faces age with more wrinkles and hair loss, influenced by both body changes and environmental factors.

Researchers found potential urine markers for polycystic ovary syndrome, including testosterone-glucuronide and 11α-hydroxyprogesterone, which may help diagnose the condition.

Taking oral testosterone with finasteride or dutasteride doubles testosterone levels, and food slightly affects it.

Lower lipin 1β in belly fat is linked to insulin resistance in people with polycystic ovary syndrome.

Isotretinoin improves severe acne without changing androgen or insulin levels but may increase body weight and triglycerides.

Advancements in male reproductive medicine are ongoing, but more research and improved treatments are needed in several areas.

Increased HSD11B1 enzyme expression is linked to higher body fat and insulin resistance.

The document concludes that Rabson-Mendenhall syndrome requires novel treatments for insulin resistance and emphasizes the importance of dental care in affected patients.

The document suggests that there might be an autoimmune link between polycystic ovary syndrome and Graves' disease.

Metformin helps manage diabetes, PCOS, and weight in kids but needs more research for long-term safety.

Hirsutism is too much hair growth in women like the pattern in men, often caused by high male hormones, and can be treated with hormone control and hair removal methods.

Taking oral testosterone with or without dutasteride increases testosterone levels and could be an effective treatment for low testosterone.

Finasteride doesn't affect oral testosterone undecanoate, and high DHT levels may cause acne, prostate issues, and hair loss.

Diagnosing PCOS in teenage girls is tricky and requires careful evaluation and management.

Hirsutism causes significant psychological distress in women.

Selective breeding caused the unique curly hair in Mangalitza pigs.

Caffeine improves hair growth, thickness, and reduces shedding.

Testosterone treatment can improve sexual function and bone density in women but may have adverse effects and requires more research on safety and guidelines.

Women with PCOS are at high risk of glucose metabolism issues and heart diseases, especially if overweight, highlighting the need for early intervention.