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400 nm particles penetrate hair follicles best, but mouse models aren't fully reliable for human studies.

Innovative methods are reducing animal testing and improving biomedical research.

Removing a specific gene in certain skin cells causes hair loss on the body by disrupting normal hair development.

Hair color production in mice is closely linked to the hair growth phase and may also influence hair growth itself.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Scientists turned rat thymus cells into stem cells that can help repair skin and hair.

Applying a specific inhibitor lightens skin and hair color.

Cysteine-rich keratins evolved independently in mammals, reptiles, and birds for hard skin structures like hair, claws, and feathers.

Stronger corticosteroids cause more skin damage in hairless dogs, similar to effects in humans.

Using neurohormones to control keratin can lead to new skin disease treatments.

IL-1 family cytokines are crucial for skin defense and healing, but their imbalance can cause skin diseases.

Anti-cancer treatments can cause reversible hair loss, skin sensitivity, pigmentation changes, nail damage, and skin reactions, with a need for more research on managing these side effects.

Thermoresponsive nanogels show promise for delivering medicine through the skin but need more safety testing and regulatory approval before clinical use.

Lanyu pigs show that partial-thickness wounds can partially regenerate important skin structures, which may help improve human skin healing.

The new gel improves skin delivery of a drug, potentially reducing dose frequency and side effects.

Thyrotropin-releasing hormone may help control skin and hair growth and could aid in treating related disorders.

Intense pulsed light treatment mainly damages pigmented hair parts but spares stem cells, allowing hair to regrow.

The document concludes that recent studies help tell apart desmoplastic trichoepitheliomas from other skin tumors, but more research is needed for clear differentiation.

Bald thigh syndrome in sighthounds is caused by structural defects in hair shafts due to downregulated genes and proteins.

Hormone imbalances from endocrine diseases can cause various skin conditions that help diagnose and treat these diseases early.

Faulty inflammasome activation may lead to autoimmune skin diseases and could be a target for new treatments.

Some vitamin D analogs can thicken skin and reduce pore size like a common acne treatment, with one analog also affecting skin growth factors.

Epidermal stem cells show promise for future dermatology treatments due to ongoing advancements.

MicroRNA-148a is crucial for maintaining healthy skin and hair growth by affecting stem cell functions.

Fractional laser therapy may help regrow hair in alopecia areata.

Immune cells are essential for early hair and skin development and healing.

Foxn1 is important for fat development, metabolism, and wound healing in skin.

Hyaluronic acid and polycaprolactone improve skin regeneration, with polycaprolactone having a stronger effect on healing and tissue repair.

The new gel for psoriasis is effective, stable, and easy to apply.