9 citations
,
March 2005 in “International Journal of Cosmetic Science” This study found that torsional measurements can effectively distinguish the effects of hair care products on the cuticle versus the cortex of hair fibers, unlike tensile measurements.
59 citations
,
August 1981 in “PubMed” This study describes trichilemmal keratinization as a distinct process of hair follicle keratinization that occurs in specific areas of the outer root sheath, illustrated using electron microscopy on dog hair.
January 2002 in “中国人民解放军军医大学学报:英文版” This study found that real-time 2-D Doppler echo of intracardiac blood flow helps evaluate myocardial infarction severity, with persistent late systolic inflow indicating worse left ventricular function.
July 2022 in “Journal of Investigative Dermatology” This study found that the KrasG12D mutation alters ERK signal dynamics in hair follicle stem cells, leading to tissue deformation, and suggests a collective effect of mutant cells is necessary for disruption.
144 citations
,
March 2013 in “Circulation Research” This study reports that mutations in the SUR2 gene are linked to Cantu syndrome, highlighting the role of KATP channels in cardiovascular health and potential new therapies.
17 citations
,
November 2017 in “Asian-Australasian journal of animal sciences” This study found that mutations in certain keratin genes significantly affect wool traits in Chinese Merino sheep, suggesting these genes could be important for sheep breeding to improve wool quality.
24 citations
,
December 1990 in “Pediatric Dermatology” This study observed that hair casts, seen in girls with tightly drawn hairstyles, may result from local circulatory disturbances and scalp inflammation.
January 2005 in “日本機械学會論文集. C編” This study suggests that minoxidil sulfate and pinacidil do not activate K channel currents in hair follicles, indicating their hair growth effects may occur through other mechanisms like increased blood flow.
22 citations
,
November 2014 in “Proteins Structure Function and Bioinformatics” In this study, researchers mapped cysteine accessibility in wool keratins and KAPs, revealing that certain cysteines in keratin end domains and Types I and II rod domains are accessible and likely involved in forming disulfide bonds.
1 citations
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August 2023 in “The journal of pharmacology and experimental therapeutics/The Journal of pharmacology and experimental therapeutics” This study developed a new method to analyze Cantú syndrome mutations in KATP channels, finding that while Kir6.1 mutations increase sensitivity to potassium channel openers, SUR2B mutations show reduced sensitivity, but both result in marked hyperpolarization compared to wild-type channels under basal conditions.
March 2025 in “International Journal of Trichology” This case study reported that a 15-year-old female developed acquired localized trichorrhexis nodosa, a hair shaft disorder, due to vigorous rubbing of an herbal powder on her scalp as part of local cultural practices.
12 citations
,
September 2013 in “BMC Biophysics” This study developed a model showing that keratin elasticity in skin may be influenced by electrostatic and bridging interactions between keratin filaments, contingent on the balance of charges in the surrounding medium.
4 citations
,
December 2018 in “Zenodo (CERN European Organization for Nuclear Research)” This study reports that in vitro experiments suggest biomagnetic cross-talk between red blood cells and human hairs as a potential factor influencing RBC deformation.
1 citations
,
October 2024 in “Journal of the American Society of Nephrology” In this case report, a patient with end stage renal disease and sickle cell trait experienced recurrent priapism episodes after starting oral minoxidil for hypertension, which resolved after discontinuing the medication, suggesting minoxidil as a potential trigger in susceptible individuals.
27 citations
,
June 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” This study identified numerous size polymorphisms in the human ultrahigh sulfur KAP4 genes due to intragenic sequence variations, suggesting these polymorphisms may have arisen through deletions and duplications during evolution.
February 1999 in “The anatomical record” This study observed defects in hair cuticle cross-linking in some, but not all, mouse mutants with sparse or structurally unsound hair.
287 citations
,
March 1999 in “The Plant Journal” This study found that disrupting the microtubule cytoskeleton in Arabidopsis root hairs caused loss of growth directionality and suggested microtubules interact with calcium gradients to regulate apical growth stability.
4 citations
,
June 2021 in “Scientific Reports” This study found that examining hair morphology provides deeper insights than classification, suggesting a potential population stratification artefact between hair curvature and cross-sectional shapes in the examined admixed African-European sample.
9 citations
,
January 2011 in “EXPERIMENTAL ANIMALS” This study describes a novel hairless mutant rat strain, F344-Hr(krh), developed via ENU mutagenesis, which provides a model for skin disease and potentially focal glomerulosclerosis due to specific genetic mutations.
10 citations
,
July 2001 in “PubMed” This case report describes two patients with a likely new type of pachyonychia, characterized by nail thickening and severe generalized hypotrichosis, possibly linked to a mutation in a hard keratin.
January 2012 in “Zhongguo shouyi xuebao” In this study, significant differences in the expression of type I IRS keratin genes were observed in the groins of three sheep breeds during wool growth, related to hair follicle density.
7 citations
,
January 2017 in “International Journal of Trichology” This case report describes a unique occurrence of plica polonica in a lung adenocarcinoma patient on chemotherapy, linked to anagen effluvium from paclitaxel and carboplatin and uncustomary shampoo use.
51 citations
,
September 2012 in “Biomacromolecules” This study found that disulfide bonds in keratin increase its strength and toughness, with some loss of α-helical structure under load, highlighting their role in trichocyte α-keratin's mechanical properties.
12 citations
,
February 2011 in “Zenodo (CERN European Organization for Nuclear Research)” This research describes methods to analyze the mechanical properties and fracture characteristics of hair across different types and ages, using specialized tensile testing and imaging techniques, without reporting new results.
12 citations
,
March 1981 in “International Journal of Dermatology” This case study reports that selenium shampoo, bacterial infection with trichomycosis axillaris, and possibly strongyloides larvae may have contributed to acquired hair shaft abnormalities resembling trichorrhexis nodosa in two patients.
4 citations
,
December 2018 in “International Journal of Research -GRANTHAALAYAH” This study reports that in vitro experiments suggest a new biomagnetic cross-talk between red blood cells and human hair could be a factor in red blood cell deformation.
July 2007 in “Manuals in biomedical research” 55 citations
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February 2014 in “Journal of Structural Biology” This study observed that human hair macrofibrils predominantly exhibit a double-twist architecture with varying inter-macrofibril angles, advancing insights into their structural organization and mechanical implications.
2 citations
,
November 2019 in “BMC urology” This study used micro-CT to visualize preputial vessel distribution in a congenital hypospadias rat model, revealing that vessels at the preputial junction with good circulation were well-suited for vascular pedicle flaps in surgery.