research Synthesis and Actions of 5α-Reduced Metabolites of Testosterone in the Nervous System
Testosterone and its metabolites affect brain functions and could help treat neurological disorders.
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210-240 / 1000+ results research Tacrolimus Monitoring in Hair Samples of Kidney Transplant Recipients
Hair samples can reliably monitor tacrolimus levels in kidney transplant patients.
research Free Testosterone Levels in Patients with COVID-19 and Its Association with Disease Severity
People with lower levels of free testosterone tend to have worse COVID-19 outcomes.
research British Society for Pediatric Dermatology Annual Meeting, Sheffield, 18-19 November 2016
The meeting highlighted the importance of genetic testing and multidisciplinary approaches in pediatric dermatology.
research Alopecias
Chronic kidney disease can cause hair loss, which may be related to zinc deficiency or certain medications, and sometimes hair grows back when the underlying issue is treated.
research S2 PSA: Reliable or Not Reliable?
PSA testing is a reliable method for detecting prostate cancer, and opioids may lower PSA levels, but triglycerides don't affect prostate cancer risk.
research S1 Opioid Receptor Agonists and Serum Prostate-Specific Antigen Level: Is There a Role for Prostate Cancer Control and Chemoprevention?
Opioid use may lower PSA levels, suggesting a possible role in prostate cancer control; PSA testing is useful for detecting prostate cancer; serum triglycerides are not linked to prostate cancer risk; and higher urethral PSA levels may be associated with local hormone activity.
research 37-Year-Old Man With Fatigue and Erectile Dysfunction
The man's fatigue and erectile dysfunction were improved by treating his obesity-related low testosterone without needing testosterone replacement.
research Non-Invasive Diagnosis of Prostate Cancer from Body Fluids Using a Panel of Tumor Suppressor Genes
Blood tests for tumor cells could improve prostate cancer diagnosis and treatment; hair loss severity linked to a gene affecting prostate conditions.
research Nephrogenic Systemic Fibrosis: Report of Two Cases
The document concludes that using gadolinium-based contrast agents during MRI can be linked to Nephrogenic Systemic Fibrosis in patients with severe kidney disease.
research Anti-Androgenic Activities of Ganoderma Lucidum
Ganoderma lucidum, a type of mushroom, may help treat enlarged prostate by blocking testosterone conversion.
research Anti-Androgenic Activities of the Triterpenoids Fraction of Ganoderma Lucidum
The triterpenoids from Ganoderma lucidum can block testosterone effects and may help treat enlarged prostate.
research Regulatory Roles of Androgens in Cutaneous Wound Healing
Testosterone may slow down wound healing and increase inflammation.
research Dihydrotestosterone Stimulates 5α-Reductase Activity in Pubic Skin Fibroblasts
Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.
research Male Androgenetic Alopecia
DHT, a testosterone byproduct, causes male pattern baldness.
research Anabolic Effects of Testosterone Are Preserved During Inhibition of 5α-Reductase
Testosterone can build muscle and bone without enlarging the prostate when a specific enzyme is blocked.
research Basics of Androgen Synthesis and Action
Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.
research The Use of Auto-Antibody Testing in the Evaluation of Interstitial Lung Disease: A Practical Approach for the Pulmonologist
Auto-antibody testing is a useful but not definitive tool in diagnosing interstitial lung diseases, and using a specific algorithm could make testing more cost-effective.
research Severe Hypertension in Children With Renal Disease: Treatment With Minoxidil
Minoxidil lowers blood pressure in kids with kidney issues, but use carefully due to side effects.
research Effects of Lespedeza Cuneata Aqueous Extract on Testosterone-Induced Prostatic Hyperplasia
Lespedeza cuneata extract may help treat enlarged prostate.
research New Insights Into Testosterone Biosynthesis: Novel Observations From HSD17B3 Deficient Mice
Mice without the enzyme HSD17B3 still produce normal testosterone, suggesting they have different ways to make it compared to humans.
research A Thallium-Based Screening Procedure to Identify Molecules That Modulate the Activity of Ca2+-Activated Monovalent Cation-Selective Channels
The conclusion is that a new test was created to find substances that affect specific ion channels, and it works well for drug discovery.
research Finasteride Inhibits 5α-Reductase Activity in Human Dermal Fibroblasts: Prediction of Its Therapeutic Application in Androgen-Related Skin Diseases
Finasteride helps treat skin issues like acne and baldness by blocking testosterone conversion.
research Testosterone Up-Regulates Vacuolar ATPase Expression and Functional Activities in Vas Deferens of Orchidectomized Rats
Testosterone increases acidification in the vas deferens by up-regulating V-ATPase.
research Anabolic and Metabolic Effects of Testosterone and Other Androgens: Direct Effects and Role of Testosterone Metabolic Products
Testosterone and its metabolites have varied effects on different body systems, especially during puberty.
research Sexual Dysfunction, Including Hypoactive Sexual Desire Disorder: Diagnosis and Treatment Recommendations
Testosterone therapy can improve sexual function in women but long-term safety is unclear.
research Supraphysiological Dose of Testosterone Impairs the Expression and Distribution of Sex Steroid Receptors During Endometrial Receptivity Development in Female Sprague-Dawley Rats
High doses of testosterone disrupt hormone levels and receptor expression in the uterus, affecting fertility.
research Sex Chromosome Related Dimorphism in Steroidogenic Enzymes and Androgen Receptor in Response to Testosterone Treatment: An In Vitro Study on Human Primary Skeletal Muscle Cells
Chromosomal differences affect how muscle cells respond to testosterone.
research Testosterone: The Male Sex Hormone
More research is needed to understand how testosterone is maintained in adult males.
research The Laboratory in the Multidisciplinary Diagnosis of Differences or Disorders of Sex Development (DSD)
Diagnosing sex development disorders requires combining medical history, physical exams, imaging, lab tests, and genetic data.