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Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.

Mitoxantrone with a corticosteroid helps manage symptoms for some advanced prostate cancer patients but doesn't extend life.

Women with PCOS often have more body hair, acne, and skin darkening, and these signs are linked to metabolic issues like insulin resistance and high cholesterol.

Nonclassic congenital adrenal hyperplasia is a genetic disorder causing hormone imbalances, affecting fertility and requiring personalized treatment.

Polycystic Ovary Syndrome can cause hair loss and skin issues, and early treatment is important for preventing complications.

Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

New treatments for enlarged prostate are being developed, some of which may be more effective than current medications.

α-spinasterol from Melandrium firmum can help reduce prostate enlargement.

International medical graduates outperformed U.S. graduates on an internal medicine exam.

Sulforaphane may help with hair growth by breaking down a hormone that causes hair loss.

LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.

The AIRE gene variant rs2075876 is linked to a higher risk of alopecia areata in males.

Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.

The enzyme 5α-reductase type 1 is important for blood vessel development and fertility in the uterus.

Activated ras can protect kidney cells from a certain substance that causes cell death.

Mutations in iRhom2 affect hair and skin in mice and are linked to esophageal cancer, with ADAM17 playing a crucial role.

Organic selenium may offer better retention and less waste in puppies.

Taking high doses of fluconazole for a long time can cause reversible hair loss.

Long-term high-dose fluconazole can cause reversible hair loss.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

Dermatologists play a key role in treating skin symptoms of PCOS like dark patches, excess hair, acne, and hair loss.

Excess androgens may cause PCOS, not just be a symptom.

Men who start puberty later may have lower sperm quality and different hormone levels in adulthood.