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A baby with maple syrup urine disease improved from skin problems by adjusting his diet to correct amino acid levels.

A woman developed severe kidney injury from using simvastatin with ciclosporin, highlighting the need for careful monitoring when combining these drugs.

The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.

Proteasome inhibitors are promising treatments for various cancers, autoimmune diseases, and other conditions.

Minoxidil boosts hair growth by opening potassium channels and increasing cell activity.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Sebocytes play a key role in controlling androgen levels in human skin.

Women with PCOS are more likely to have impaired glucose tolerance and type 2 diabetes, especially if they are Asian or obese.

Laser device increases hair density, safe for treating hair loss in men and women.

Postpartum depression is linked to changes in brain chemicals, inflammation, stress, and certain genes, and can potentially be identified by markers like specific steroids, serotonin levels, and vitamin D levels.

Finasteride effectively blocks enzyme causing male pattern baldness.

New compounds were made that block an enzyme linked to breast cancer better than existing treatments.

Finasteride effectively blocks rat enzymes, but with varying methods and strength.

Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.

DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.

Best hair growth results from combining finasteride and minoxidil.

Norgestimate is the most effective birth control progestin for reducing an enzyme linked to acne and excessive hair growth in women.

Hair color loss can indicate the effectiveness of a drug targeting the KIT protein in mice and humans.

The document says to treat cat fungal infections with medicine and clean the environment, noting that cats without symptoms can still spread it to humans.

Finasteride slowly binds to 5-alpha-reductase, affecting enzyme stability and inhibitor potency.

Dandruff is a common, winter-worsened scalp condition linked to inflammation and microorganisms, treatable with products like ketoconazole, and may affect hair loss.

Human hair follicles can make and process prostaglandins, which may affect hair growth.

Finasteride almost fully depletes allopregnanolone in rat brains and enhances 20α-DHP, but doesn't change 3α-DHP levels.

Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Certain drugs that block specific enzymes can help treat prostate diseases.

Finasteride helps treat hair loss and prostate enlargement by blocking a specific enzyme.