Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This review discusses the history and development of keratin biomaterials for biomedical uses, highlighting their biological activity and biocompatibility, and provides no new research findings.

Human hair keratin can be used in many medical applications.

This paper critically reviews recent advances in the use of keratin-based biomaterials, highlighting their potential applications in wound healing, drug delivery, and tissue regeneration due to their biocompatibility, biodegradability, and ability to support cell growth.

This study found that the binding and release of BMP-2 from kerateine biomaterials are significantly influenced by pH and salt concentration, highlighting the potential for developing improved bone repair systems.

This study highlights keratin biomaterials as a promising biocompatible option for wound healing and tissue regeneration but notes that further clinical studies are necessary to confirm their effectiveness.

Human hair keratin hydrogels show promise for use in regenerative medicine.

This study utilized advanced imaging techniques to quantify hair damage and dye uptake dynamics, revealing that compound penetration in hair is influenced by molecule size and lipophilicity.

This study characterized keratin-based biomaterials that self-assemble into hydrogels, demonstrating their potential to achieve hemostasis in a lethal liver injury model through specific biomaterial-receptor interactions.

This study observed that hepatocyte adhesion to human hair keratin biomaterials was mediated by the hepatic ASGPR, as blocking this receptor reduced cell attachment.

This study demonstrated that a keratin gel promotes nerve regeneration across critical defects in rabbit models, showing improved nerve conduction and muscle action potential compared to control treatments.

This study found that the internal structure and fracture patterns of hair vary among different mammal species, which could inform the development of keratin-based biomaterials for medical and cosmetic applications.

This study observed that increasing the γ-kerateine content in meta-kerateine materials led to reduced elasticity, solidity, and hydrolytic stability, and decreased hepatocyte attachment support.

This review discusses the structure and regenerative potential of hair follicles, highlighting their role in wound healing, stem cell populations, and keratin-based biomaterials, but it reports no new clinical results.

This review discusses the properties and extraction methods of keratins from natural fibers and highlights their promising applications in fields such as biomedicine, bioengineering, and forensic science, but reports no new experimental results.

This study reports that keratin-based materials derived from human hair have potential for use in tissue engineering, showing promising bioactivity and mechanical support in preliminary evaluations.

This research describes methods to analyze the mechanical properties and fracture characteristics of hair across different types and ages, using specialized tensile testing and imaging techniques, without reporting new results.

In this study, researchers developed a novel periodate oxidation method for extracting keratin micro-units from waste hair and feathers, achieving yields of 31.28% and 20.64% respectively, enhancing the stability of oil-in-water emulsions and suggesting potential for sustainable biomaterial production.

This review discusses the role of hair follicles in wound healing and scar remodeling, emphasizing that hair follicle transplantation may aid in faster wound closure and scar reduction by enhancing the cellular and molecular mechanisms involved in scarring.

This study systematically analyzed the molecular and cellular mechanisms of wound healing and assessed the market potential for wound healing products based on natural proteins, projecting significant growth by 2033.

This study observed that keratin-based microspheres promoted hair regrowth in C57BL/6 male mice and enhanced hair growth markers in human dermal papilla cells, suggesting these particles may effectively target hair follicles to aid in hair growth.

In this study, the researchers found that a keratin hydrogel filler in nerve conduits led to earlier Schwann cell migration and improved cellular behaviors compared to other fillers in a rat sciatic nerve model.

This study found that alkylation of kerateine cysteine residues created a cell-compatible method for controlling hydrogel erosion rates and therapeutic agent release in keratin-based systems.

This study found that keratin-based particles were able to recover and enhance the mechanical properties and thermal stability of virgin and overbleached Asian hair, improving its strength and smoothness by around 40%, and demonstrated safety in human skin keratinocytes.

In this study, a keratin hydrogel improved survival rates and functional recovery in rats with spinal cord injuries, suggesting potential for SCI treatment that merits further investigation.

Keratin-based hydrogels from human hair improve wound healing effectively.

In a study on diabetic mice, researchers developed a protein-based hydrogel that leverages zinc ions and the natural compound phellopterin to promote cutaneous nerve regeneration, angiogenesis, and tissue remodeling in diabetic wounds, highlighting its potential for advanced wound therapy.

This study extracted water-soluble keratin particles from chicken feathers and verified their structural properties, observing no irritative potential on hen's eggs and positive physiological effects on human skin cells, suggesting their suitability for use on damaged or irritated skin.

In this study, keratin‐based hydrogels incorporating calcium ions were developed to effectively deliver atorvastatin, showing potential for localized anti‐fibrotic therapy through controlled drug release and maintaining drug bioactivity in vitro, supported by thorough physicochemical and mechanical characterization.

This study found that a biomaterial gel made from human hair keratins facilitated nerve regeneration in an animal model, potentially matching the effectiveness of traditional autografts.

In this review, researchers reported that incorporating nanoparticles into natural-based biomaterials enhanced scaffolding properties, cellular interactions, and outcomes in wound healing, with promising implications for tissue engineering and regenerative medicine, although many signaling pathways involved are still not fully understood.