In Vitro Analysis of Hemostatic Efficacy of Fibrinogen Precipitation With Varied Keratin Fraction Compositions

    June 2023 in “ International journal of biological macromolecules ”
    Wei-Chieh Chen, Nan-Kai Hsieh, Meng Huang … Yang Wei
    Studysummary In this preclinical study, researchers found that combining equal ratios of high molecular weight keratin intermediate filaments and low molecular weight keratin-associated proteins from human hair led to the most extensive fibrinogen precipitation, suggesting potential for developing effective hair protein-based hemostatic materials.
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    Research cited in this study 14

    1. Keratin-Associated Protein Nanoparticles as Hemostatic Agents ACS applied nano materials · 2021
    2. Effect of Varied Hair Protein Fractions on the Gel Properties of Keratin/Chitosan Hydrogels for Use in Tissue Engineering Colloids and surfaces. B, Biointerfaces · 2020
    3. Effect of Thermal Treatments on the Structural Change and Hemostatic Property of Hair Extracted Proteins Colloids and surfaces. B, Biointerfaces · 2020
    4. Raman Spectroscopy and Electronic Microscopy Structural Studies of Caucasian and Afro Human Hair Heliyon · 2019
    5. Recombinant Human Hair Keratin Proteins for Halting Bleeding Artificial Cells Nanomedicine and Biotechnology · 2018
    6. Types I and II Keratin Intermediate Filaments Cold Spring Harbor Perspectives in Biology · 2018
    7. Characterization of the Promoter Regions of Two Sheep Keratin-Associated Protein Genes for Hair Cortex-Specific Expression PloS one · 2016
    8. Human Hair Keratin and Its-Based Biomaterials for Biomedical Applications Jo'jig gonghag gwa jaesaeng uihag/Tissue engineering and regenerative medicine · 2014
    9. Hemostatic Properties and the Role of Cell Receptor Recognition in Human Hair Keratin Protein Hydrogels Biomaterials · 2013
    10. A Novel Purification Procedure for Keratin-Associated Proteins and Keratin from Human Hair Journal of Biological Macromolecules · 2013
    11. A Review of Keratin-Based Biomaterials for Biomedical Applications Materials · 2010
    12. A Cluster of 21 Keratin-Associated Protein Genes Within Introns of Another Gene on Human Chromosome 21q22.3 Genomics · 2004
    13. A Rapid Extraction Procedure of Human Hair Proteins and Identification of Phosphorylated Species Biological and Pharmaceutical Bulletin · 2002
    14. Identification of Differentially Expressed Genes During a Wool Follicle Growth Cycle Induced by Prolactin Journal of Investigative Dermatology · 1999