Human Hair Keratin-Based Hydrogels in Regenerative Medicine: Current Status and Future Directions

    September 2023 in “ ACS Biomaterials Science & Engineering ”
    Mymuna Ashna, Neeharika Senthilkumar, Pallab Sanpui
    Image of study
    TLDR Human hair keratin hydrogels show promise for use in regenerative medicine.
    Regenerative medicine (RM) uses the regenerative potential of human cells to create functional human cells, tissues, and organs. A key component of RM is a biomaterial scaffold with the right physicochemical properties. Hydrogels, which can be made from synthetic polymers or biopolymers, have become a popular choice for tissue engineering and RM applications. They can be used as scaffolds for spatial patterning, delivering therapeutic agents, or substrates to enhance cell growth, differentiation, and migration. Biopolymers are preferred for their biocompatibility. Keratins, fibrous proteins, have recently been used to construct hydrogels for RM. This review focuses on the use of human hair keratin hydrogels in various RM applications.
    Discuss this study in the Community →

    Research cited in this study

    10 / 10 results

    Related Community Posts Join

    6 / 230 results

      community Verteporfin and Microneedling

      in Treatments 6 months ago
      Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.

      community Has anyone else seen this encouraging verteporfin case study?

      in Progress Pictures  38 upvotes 1 year ago
      The conversation discusses the potential use of verteporfin for hair loss treatment, with one user mentioning their surgeon's interest in trying it and another noting its research status and clinical use as a YAP inhibitor. Some users debate the market size, availability of generics, and the optimism in the hair loss community regarding new treatments.

      community Why isn’t anyone talking about this?

      in Research/Science  31 upvotes 10 months ago
      Hair cloning is being developed by companies like Kangstem Biotech and Stemson, with potential availability in a few years. Initial costs are expected to be high, but prices may decrease over time.

      community New and Interesting HairLoss Studies/Papers/Reviews

      in Treatment  42 upvotes 4 years ago
      Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

      community Had a rough week. What to do now?

      in Treatment  36 upvotes 4 months ago
      The user had a rough week after being told they couldn't get a hair transplant due to insufficient donor area and worsening balding. They were advised to increase their oral Minoxidil dosage and consider switching from Finasteride to Dutasteride.

    Similar Research

    5 / 1000+ results