Human Hair Keratin-Based Hydrogels in Regenerative Medicine: Current Status and Future Directions

    Mymuna Ashna, Neeharika Senthilkumar, Pallab Sanpui
    Image of study
    TLDR Human hair keratin hydrogels show promise for use in regenerative medicine.
    Regenerative medicine (RM) uses the regenerative potential of human cells to create functional human cells, tissues, and organs. A key component of RM is a biomaterial scaffold with the right physicochemical properties. Hydrogels, which can be made from synthetic polymers or biopolymers, have become a popular choice for tissue engineering and RM applications. They can be used as scaffolds for spatial patterning, delivering therapeutic agents, or substrates to enhance cell growth, differentiation, and migration. Biopolymers are preferred for their biocompatibility. Keratins, fibrous proteins, have recently been used to construct hydrogels for RM. This review focuses on the use of human hair keratin hydrogels in various RM applications.
    Discuss this study in the Community →

    Research cited in this study

    16 / 16 results

    Related Community Posts Join

    6 / 388 results

      community Verteporfin and Microneedling

      in Treatments 1 year ago
      Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.

      community Update and new paper from Dr tsuji

      in Update  24 upvotes 6 years ago
      Hair follicle regenerative therapy is being developed, with clinical trials planned in Japan, potentially allowing for hair cloning and eliminating the need for treatments like finasteride. If successful, the treatment could be available in Japan by 2025, but widespread access and affordability may take longer.

      community Riken develops new method for culturing hair follicles

       38 upvotes 7 years ago
      A new stem cell method for culturing hair follicles is being developed as an alternative to Minoxidil, finasteride, and RU58841. There are concerns about its cost and accessibility despite plans for commercialization.

      community Federal Grant Cuts have impacted PP405 related research

      in Technology  459 upvotes 5 months ago
      Federal funding cuts have delayed PP405 research, affecting hair loss treatment progress, though clinical trials will continue. The discussion highlights PP405's potential compared to minoxidil and finasteride and stresses the importance of government-funded research.

      community Any MD/DO’s in this subreddit?

      in Research/Science  10 upvotes 10 months ago
      The conversation discusses hair loss treatments, specifically Minoxidil, finasteride, and RU58841. The user seeks input from medical professionals and scientists on these treatments.

      community Has anyone else seen this encouraging verteporfin case study?

      in Progress Pictures  35 upvotes 2 years ago
      The conversation discusses the potential use of verteporfin for hair loss treatment, with one user mentioning their surgeon's interest in trying it and another noting its research status and clinical use as a YAP inhibitor. Some users debate the market size, availability of generics, and the optimism in the hair loss community regarding new treatments.

    Similar Research

    5 / 1000+ results