44 citations,
July 2016 in “Stem Cells Translational Medicine” Scientists discovered that certain stem cells from mice and humans can be used to grow new hair follicles and skin glands when treated with a special mixture.
38 citations,
July 2020 in “EMBO journal” SIRT7 protein is crucial for starting hair growth in mice.
191 citations,
September 2011 in “Cell stem cell” Hair follicle stem cells use specific chromatin changes to control their growth and differentiation.
29 citations,
January 2017 in “Journal of Investigative Dermatology” The Msi2 protein helps keep hair follicle stem cells inactive, controlling hair growth and regeneration.
New treatments for hair loss show promise, including plasma, stem cells, and hair-stimulating complexes, but more research is needed to fully understand them.
11 citations,
June 2021 in “Frontiers in Cell and Developmental Biology” Melatonin helps goat hair stem cells grow and maintain their ability to become different cell types.
November 2024 in “Journal of Translational Internal Medicine” Exosomes from stem cells help hair regrowth by activating a specific signaling pathway.
18 citations,
January 2017 in “Annals of dermatology/Annals of Dermatology” Certain immune cells contribute to severe hair loss in chronic alopecia areata, with Th17 cells possibly having a bigger impact than cytotoxic T cells.
46 citations,
June 2015 in “Journal of Investigative Dermatology” Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.
32 citations,
May 2018 in “Cell Cycle” Melatonin helps Cashmere goats grow more hair by affecting certain genes and cell pathways.
November 2015 in “European Journal of Inflammation” Cicatricial alopecia, a permanent hair loss condition, is mainly caused by damage to specific hair follicle stem cells and abnormal immune responses, with gene regulator PPAR-y and lipid metabolism disorders playing significant roles.
13 citations,
May 2022 in “Cell discovery” The study found new details about human hair growth and suggests that preventing a specific biological pathway could potentially treat hair graying.
170 citations,
July 2012 in “Journal of Investigative Dermatology” Wnt ligands are crucial for hair growth and repair.
326 citations,
February 2009 in “The American journal of pathology” Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.
14 citations,
January 2011 in “Journal of Cutaneous Pathology” CK15 is not a reliable marker for stem cells in damaged hair follicles from patients with CCCA.
1 citations,
November 2022 in “Journal of Investigative Dermatology” ALRN-6924 may prevent hair loss caused by chemotherapy.
14 citations,
April 2021 in “International journal of molecular sciences” Mesenchymal stem cells may help treat hair loss by improving hair cell growth and reducing inflammation.
137 citations,
April 2015 in “Nature Reviews Molecular Cell Biology” Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.
9 citations,
April 2019 in “Molecules” Blackcurrant extract may help reduce hair loss by promoting stem cell activity in hair follicles.
4 citations,
January 2022 in “Life” Tissue engineering could be a future solution for hair loss, but it's currently expensive, complex, and hard to apply in real-world treatments.
November 2023 in “Nature Communications” Cells lacking the Bax protein can outcompete others, leading to better tissue repair and hair growth.
36 citations,
January 2019 in “Nature communications” High lactate dehydrogenase activity is not necessary for the growth of squamous cell carcinoma.
2 citations,
August 2016 in “Lasers in Surgery and Medicine” Photodynamic therapy can remove nonpigmented hair in mice and might work for humans.
32 citations,
July 2017 in “Wiley Interdisciplinary Reviews-Developmental Biology” Transit-amplifying cells are crucial for tissue repair and can contribute to cancer when they malfunction.
TLR2 helps control hair growth and regeneration, and its reduction with age or obesity can impair hair growth.
22 citations,
June 2017 in “Stem cell reports” PTEN helps control the number and health of skin stem cells by working with the protein BMAL1.
665 citations,
April 2016 in “Nature communications” Blocking specific proteins can help remove aging cells and might treat age-related diseases and promote hair growth.
65 citations,
January 2018 in “Nature Reviews Endocrinology” Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.
September 2014 in “Aktuelle Dermatologie” The symposium concluded that environmental factors significantly contribute to skin aging.
5 citations,
January 2021 in “Frontiers in cell and developmental biology” Skin cysts might help advance stem cell treatments to repair skin.