10 citations
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September 2024 in “Journal of Nanobiotechnology” This study developed an antimicrobial microneedle patch for delivering apoptotic vesicles to treat infected wounds, which was found to effectively reduce bacterial growth and accelerate scarless healing, including the rapid formation of mature hair follicles in just 8 days, a previously unreported early outcome.
October 2025 in “Cell Proliferation” In laboratory research, investigators found that apoptotic vesicles from interleukin-10-treated fibroblasts promote wound healing and reduce fibrotic scarring by enhancing mitochondrial function, modulating collagen composition, and inhibiting the Hedgehog signalling pathway, offering potential for regenerative medicine applications.
21 citations
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January 2023 in “Biomaterials Science” This study investigated the use of dissolving microneedle patches to improve the skin-lightening effects of alpha-arbutin and resveratrol, finding that the patches enhanced intradermal delivery and slightly decreased the melanin index without affecting skin hydration or causing irritation over 24 hours.
14 citations
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September 2024 in “Cosmetics” This narrative review explores how exosomes and cell culture-conditioned media are becoming key players in the cosmetic industry for skin rejuvenation and prejuvenation, emphasizing their multifunctional topical benefits and potential future applications.
6 citations
,
September 2019 in “Skin pharmacology and physiology” This study found that RCS-01 cell therapy for aged skin was well tolerated and associated with increased gene expression related to extracellular matrix homeostasis, suggesting potential skin improvement.
This study explores autologous cell-based therapy using dermal sheath cup cells for pattern hair loss in a randomized, placebo-controlled clinical trial and reports no new clinical results.
October 2017 in “Journal of Investigative Dermatology Symposium Proceedings” This study suggests that PGD2 may increase testosterone production in keratinocytes through oxidative stress pathways, with n-acetyl-cysteine blocking this effect.
24 citations
,
January 2017 in “International Journal of Trichology” December 2018 in “Dermatologic Surgery” This overview describes the Dermatologic Surgery journal's comprehensive focus on cosmetic and reconstructive skin procedures, but it reports no new research findings.
22 citations
,
April 2022 in “Stem cell research & therapy” This study found that extracellular vesicles derived from hair follicle mesenchymal stromal cells demonstrated similar potential to those from adipose tissue in promoting cell proliferation and migration, enhancing angiogenesis, and protecting cells under stress, suggesting promise for chronic wound treatment.
10 citations
,
September 2021 in “International Journal of Nanomedicine” This review explores the potential diagnostic and therapeutic applications of extracellular vesicles in treating various skin conditions but reports no new clinical study results.
March 2024 in “EMBO molecular medicine” This study found that the antiviral drug daclatasvir significantly improved fibrosis and quality of life in a mouse model of recessive dystrophic epidermolysis bullosa, suggesting potential for treating this and other fibrotic diseases.
26 citations
,
June 1993 in “Archives of Otolaryngology - Head and Neck Surgery” This study found that the endolaser technique using a small incision is as effective as standard forehead lifts for reducing glabellar frown lines and forehead creases with a shorter recovery time.
92 citations
,
June 2017 in “Journal of Plastic Reconstructive and Aesthetic Surgery” This review found that microneedling appears to be a safe and effective option for treating scars and wrinkles, with fewer side effects and shorter recovery time than some other treatments.
11 citations
,
January 2011 in “Journal of Cutaneous and Aesthetic Surgery” This study on a 30-year-old male reported that single-hair follicular unit transplant effectively repigmented a stable vitiligo patch, achieving complete pigmentation in 8 weeks with no recurrence after 6 months.
1 citations
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November 2020 in “Dermatologic Surgery” Using combined hair restoration methods can effectively treat severe scalp wrinkling.
September 2025 in “International Journal of Innovative Technologies in Social Science” This study reviewed aesthetic gynecology procedures, reporting that most are safe, well tolerated, and yield high patient satisfaction, particularly for postmenopausal and postpartum women. However, the study highlights the need for standardized protocols and long-term data.
1 citations
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February 2024 in “Journal of nanobiotechnology” This review explores how combining extracellular vesicles with hydrogels and utilizing 3D bioprinting technologies creates innovative composite systems for wound healing, offering advanced mechanical and biological support, while addressing challenges like degradation and regulatory issues in clinical applications.
3 citations
,
May 2025 in “Frontiers in Pharmacology” This study identified known and potential novel adverse events, such as squamous cell carcinoma and dehydration, for vismodegib, underlining the importance of monitoring especially in the first two months of treatment.
1 citations
,
April 2021 in “Aesthetic Cosmetology and Medicine” This article reviews various applications and substances in mesotherapy for skin conditions and discusses the benefits of series treatments, reporting no new clinical results.
5 citations
,
January 2012 in “Journal of Tissue Science & Engineering” In this study, collagen I decellularized scaffolds enhanced the growth and melanotic properties of hair follicle melanocytes, suggesting their potential as effective carriers for transplantation in vitiligo treatment.
1 citations
,
August 2021 in “Pediatrics in review” This case report describes a rare instance of labial hair tourniquet syndrome in a 10-year-old girl, emphasizing the importance of considering this condition in the differential diagnosis of vulvar lesions.
1 citations
,
August 2019 in “IntechOpen eBooks” This article discusses the use of mesotherapy in dentistry and reports no new clinical results, emphasizing the need for further research on its applications for oral problems.
28 citations
,
December 1999 in “British Journal of Plastic Surgery”
41 citations
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September 2017 in “Advanced Healthcare Materials” This study found that the DexIEME hydrogel promotes complete skin regeneration and scar attenuation in murine and porcine models, suggesting potential for treating deep dermal injuries.
June 2025 in “Journal of Cosmetic Dermatology” This study reports that autologous micrografting may effectively treat stretch marks by promoting extracellular matrix remodeling and enhancing fibroblast activity, potentially expanding therapeutic options for this condition.
2 citations
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February 2025 in “Journal of Cosmetic Dermatology” In a randomized clinical trial presented in this study, a novel lip hydrant with polyherbal extracts significantly reduced lip roughness and chapped lips compared to petroleum gel over 28 days among Thai participants, although both treatments improved perceived lip dryness.
February 2026 in “Plastic and Aesthetic Research” This narrative review examines advancements in regenerative aesthetic medicine, focusing on injectable modalities like PRP, polynucleotides, and exosomes, but highlights the need for more robust evidence and standardization in clinical applications.
July 2023 in “International journal of dermatology, venereology and leprosy sciences” This review discusses micro needling as a therapeutic option for various dermatological conditions, such as scars and pigmentation, and reports no new clinical results; the authors note potential side effects and contraindications.
106 citations
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January 2016 in “Journal of Cosmetic Dermatology” This study found that adding platelet-rich plasma to microneedling improved outcomes for atrophic acne scars more than microneedling alone, according to both quantitative and qualitative assessments.