Effectiveness of an Autologous Micrografting Technology for Treating Stretch Marks

    June 2025 in “ Journal of Cosmetic Dermatology ”
    Andrea Garelli, Valeria Pessei, Ruggero Tagliabue, Olha Sles, Ratchathorn Panchaprateep
    From the encyclopedia
    Microneedling →

    technique to create small wounds in skin to activate collagen production and hair growth

    collagen →
    Studysummary This study reports that autologous micrografting may effectively treat stretch marks by promoting extracellular matrix remodeling and enhancing fibroblast activity, potentially expanding therapeutic options for this condition.
    Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
    The study assessed the effectiveness of autologous micrografting technology, specifically Rigenera Technology, in treating stretch marks in 14 patients over 9 months. The procedure involved microneedling and injecting micrografts from the patient's tissue into stretch marks. Photographic assessments and in vitro tests indicated changes in collagen and elastin gene expression, suggesting skin remodeling improvements. The study concluded that this minimally invasive technique could be promising for treating stretch marks, with significant improvements in appearance and texture, high patient satisfaction, and no severe adverse effects. However, the small sample size calls for further research with larger groups to confirm these findings and evaluate long-term effects.
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