Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

Tofacitinib 2% ointment helped hair regrow in 3 out of 10 patients with alopecia areata, but caused side effects like scalp irritation and raised cholesterol in some.

This study systematically reviewed clinical findings in trichothiodystrophy patients and suggested a new clinico-genetic classification to help better understand the ichthyotic phenotype and its management.

In this randomized, placebo-controlled study, Titagen® was found to improve skin, hair, and nail health in adults consuming 5g daily, and reduce pain and improve quality of life for osteoarthritis patients taking 10g daily, without related adverse events.

This study found significant improvements in hair growth parameters and a reduction in hair fall after using the test product for 90 days, with no adverse events reported.

This study reported four new cases of NISCH syndrome in a Moroccan family, confirming genetic variability in liver disease severity and suggesting potential benefits from early UDCA therapy.

In this nonrandomized controlled trial, tenon capsule injection of platelet-rich plasma improved capillary perfusion and may enhance short-term vision in patients with acute nonarteritic anterior ischemic optic neuropathy.

This narrative review and case report identified a rare association between erythema nodosum and kerion caused by *Trichophyton mentagrophytes*, with successful treatment using antifungals and corticosteroids.

This case report details the first use of baricitinib in a pediatric patient with immune thrombocytopenia and alopecia areata, showing successful treatment with increased platelet counts.

In this study, the researchers found that the absence of the NFI-C transcription factor delayed the hair growth cycle in mice by affecting key gene expressions and signaling pathways.

In this study, hair follicle transcriptomic responses to a 10-day HIIT program revealed both existing and new biomarkers, such as certain miRNAs, offering a potentially effective way to monitor cellular and molecular HIIT adaptations.

TICE salvage chemotherapy is effective for treating germ-cell tumors with poor prognosis.

This study found that combining a thulium laser with intra-perifollicular PDRN injections significantly improved hair thickness but not hair counts compared to mesotherapy and PDRN in patients with pattern hair loss.

Certain immune cells in atopic dermatitis skin could be targeted for treatment.

This study found that terbinafine prevented the invasion of keratin by Trichophyton mentagrophytes in experimental models replicating human dermatomycoses.

This study observed that human anagen hair follicles can grow in vitro when maintained serum-free, with possible implications for understanding hair follicle growth mechanisms.

In this case report, a woman with Graham-Little-Piccardi-Lassueur Syndrome and hidradenitis suppurativa showed significant improvements in both conditions after six months of treatment with tofacitinib, a Janus Kinase inhibitor, with no recurrence or adverse events noted during a two-year follow-up.

In this case report, a young adult male with resistant alopecia areata showed nearly 90% hair regrowth after 3 months of treatment with tofacitinib, alongside biotin supplementation, without any side effects observed.

Natubiotin is effective for treating different hair loss conditions when used with other therapies.

This article reviews cultural differences in the incidence of hair-thread tourniquet syndrome and finds it may be less prevalent in Iranian children compared to Europe, possibly due to social and cultural factors.

This study developed a straightforward HPTLC method for detecting nicotine and cotinine in human plasma and urine, concluding that liquid-liquid extraction with methanol: chloroform: ammonia achieved optimal separation and is applicable for forensic analysis of lethal nicotine intoxication.

This case report presents an HIV-1 patient who experienced osteosclerosis and new bone formation potentially due to long-term indinavir therapy and concurrent use of vitamin A, with symptoms reducing after switching to nelfinavir.

This study found variation in erythema induction across skin types, suggesting different SSR dose responses and highlighting a potential model for tailoring anti-inflammatory treatments.

This review discusses the concept and treatment of diffuse hair loss, known as Intithār al-Sha‘r, in the Unani system, drawing from classical Unani literature without reporting new clinical results.

This study reviewed recent advancements in using botulinum toxin for treating androgenetic alopecia and emphasized the need for further research to determine the most effective injection sites and depths, as current strategies show inconsistent results.

In a retrospective study, TNFα inhibitor-induced alopecia was observed in pediatric patients, primarily adolescents with inflammatory bowel diseases, with hair regrowth occurring in those who discontinued the therapy; this suggests that stopping these medications can improve drug-induced alopecia in children.

This study found that oral tofacitinib led to variable hair regrowth in patients with resistant alopecia areata, implying that longer treatment durations may be needed to fully assess its effectiveness.

In this study, researchers developed topical tofacitinib-loaded cationic lipid nanoparticles, which improved absorption and targeted hair follicles in an ex vivo pig ear model, showing promise in treating alopecia areata by reducing symptoms through the JAK/STAT pathway.

In this case report, the researchers described the use of tofacitinib in treating a 14-year-old boy from India with severe alopecia areata, achieving complete hair regrowth within 2 months without serious adverse events, highlighting tofacitinib's potential benefits and safety in adolescent cases.