Efficacy and Safety of Platelet-Rich Plasma for Acute Nonarteritic Anterior Ischemic Optic Neuropathy: A Prospective Cohort Study

March 2024 in “ Frontiers in medicine ”

Xin Jin, Junxia Fu, Ruihua Lv, Xiaolu Hao, Song Wang, Mingming Sun, Guangcan Xu, Qi Zhang, Lei Zhang, Yan Li, Quangang Xu, Baoke Hou

platelet-rich plasma PRP

TLDR PRP treatment can safely improve short-term vision in acute NAION patients.

This study evaluated the efficacy and safety of platelet-rich plasma (PRP) for treating acute nonarteritic anterior ischemic optic neuropathy (NAION) in 25 patients. The PRP group (12 patients) received two tenon capsule injections of PRP, while the control group (13 patients) received standard treatment. Results showed that the PRP group had a significant improvement in best-corrected visual acuity (BCVA) and capillary perfusion density (CPD) at 30 days post-treatment. The main adverse effect was local discomfort, which resolved within a week. Overall, PRP was found to be a safe treatment that could enhance capillary perfusion and potentially improve short-term vision in acute NAION patients.

View this study on frontiersin.org →

Discuss this study in the Community →

Research cited in this study

2 / 2 results

research Applications of the Regenerative Capacity of Platelets in Modern Medicine

60 citations, December 2021 in “Cytokine & growth factor reviews”

PRP therapy shows promise in healing and tissue repair across various medical fields but needs more research for standardization and optimization.

research Platelet-Rich Plasma for Hair Restoration

16 citations, March 2020 in “Facial Plastic Surgery Clinics of North America”

Platelet-Rich Plasma (PRP), a substance from a patient's own blood, can stimulate hair regrowth in people with Androgenetic Alopecia (AGA) who haven't had success with other treatments, but more research is needed to optimize its use.

Similar Research

6 / 1000+ results

Introducing Platelet-Rich Stroma: Platelet-Rich Plasma and Stromal Vascular Fraction Combined for the Treatment of Androgenetic Alopecia

research Introducing Platelet-Rich Stroma: Platelet-Rich Plasma and Stromal Vascular Fraction Combined for the Treatment of Androgenetic Alopecia

40 citations, March 2018 in “Aesthetic Surgery Journal”

New treatment combining PRP and SVF increases hair density in 6-12 weeks for androgenetic alopecia patients.

research Successful Treatment of Corticosteroid-Resistant Ophiasis-Type Alopecia Areata with Platelet-Rich Plasma

30 citations, August 2015 in “JAAD case reports”

Platelet-rich plasma (PRP) injections successfully treated a woman's steroid-resistant hair loss, causing hair to regrow within a month.

research Platelet-Rich Plasma: Current Applications in Dermatology

25 citations, September 2019 in “PubMed”

Platelet-Rich Plasma (PRP) is helpful for skin and hair treatments and works better when combined with other procedures.

research The Effects of Lower vs Higher Cell Number of Platelet-Rich Plasma on Hair Density and Diameter in Androgenetic Alopecia: A Randomized, Double-Blinded, Placebo, Parallel-Group Half-Scalp IRB-Approved Study

6 citations, May 2021 in “Aesthetic Surgery Journal”

Higher cell number PRP improves hair density and diameter more than lower cell number PRP.

research Platelet-Rich Plasma in Dermatology: Cellular and Molecular Mechanisms of Action

3 citations, December 2023 in “Biomedicines”

PRP therapy helps skin heal and improve by promoting cell growth and repair.

research Notes from the Editor Emeritus: Platelet Rich Plasma in Patients with Androgenetic Alopecia: Does It Work?

2 citations, January 2014 in “Hair transplant forum international”

Platelet Rich Plasma (PRP) therapy can improve hair thinning in male pattern baldness patients, but more research is needed to confirm its effectiveness.

Efficacy and Safety of Platelet-Rich Plasma for Acute Nonarteritic Anterior Ischemic Optic Neuropathy: A Prospective Cohort Study

Research cited in this study

research Applications of the Regenerative Capacity of Platelets in Modern Medicine

research Platelet-Rich Plasma for Hair Restoration

Related Community Posts Join

community Do Platelet-rich plasma, PRP work?

community Why can't you drink caffeine after PRP?

community I just made my own PRP - DIY PRP

community Anyone have PRP/Exosome results to share?

community Most Recent Interesting Hairloss Studies: 10% Minox vs 5% Minox / Radio Rrequency Treatment for AA / Topical Ketoconazole / PRP+Minox vs Minox vs PRP / Alopecia as a systemic disease

community 1.5 Year Hair Restoration Journey - Stem Cells, PRP, Minoxidil, Topical Finasteride