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This study found that adipose-derived stem cell-conditioned media improved skin flap survival following ischemia/reperfusion injury in mice by increasing cell proliferation and the number of hair follicles, mediated by IL-6.

This study found that hair follicle stem cell-derived secretome mitigated cell death, apoptosis, and inflammation while upregulating neurotrophic factors in astrocytes exposed to oxygen-glucose deprivation, an in vitro ischemic stroke model, suggesting potential therapeutic benefits in stroke recovery.

This study found that inducing SOX2 in keratinocytes significantly reduced pressure ulcer formation after cutaneous ischemia-reperfusion injury by producing amphiregulin, which also reduced oxidative stress and apoptosis.

This review discusses the potential of optical techniques for diagnosing and treating oxidative stress-related hepatic ischemia-reperfusion injury, highlighting the need for non-invasive diagnostic methods and the anti-oxidative potential of optical therapies; it reports no new clinical results.

This study suggests that hair follicle mesenchymal stem cells may alleviate small intestinal ischemia-reperfusion injury in rats by promoting angiogenesis, reducing apoptosis, and enhancing intestinal stem cell expression.

This study found that injecting hepatocyte growth factor-enhanced hair follicle stem cells into a rat model of ischemic stroke improved recovery by reducing inflammation, protecting the blood-brain barrier, and promoting angiogenesis.

This study found that while testosterone administration reduced myocardial damage in gonadectomized rats after ischemia/reperfusion injury, Finasteride led to greater improvements, whereas 4-hydroxyandrostenedione worsened outcomes.

This study suggests that hair follicle mesenchymal stem cells may alleviate small intestinal ischaemia-reperfusion injury in rats by promoting angiogenesis, reducing apoptosis, and protecting intestinal mucosal function.

Dexpanthenol helps protect the brain and improve motor skills after a stroke.

Hair follicle stem cells may help repair the brain after a stroke.

This study found that hair follicle stem cells, when transplanted in a rat model of ischaemic stroke, migrated to affected areas, expressed neuron-specific markers, and reduced infarct volume, suggesting potential therapeutic benefits.

This study found that hair follicle stem cell transplantation in a rat model of ischaemic stroke reduced infarct volume and promoted neurological recovery, suggesting potential therapeutic benefits for stroke treatment.

In this study, transplantation of rat hair follicle stem cells was associated with reduced infarct volume and enhanced neurological recovery after ischaemic stroke, suggesting therapeutic potential for further clinical development.

This study found that minoxidil provides cardioprotective effects in guinea-pig heart cells through selective activation of mitochondrial ATP-sensitive potassium channels.

This review explores factors affecting graft growth and survival in hair restoration, emphasizing the importance of fundamental care practices while considering advanced storage solutions and additives, but reports no new findings.

In this study, azelaic acid 20% and finasteride increased BCL-2 protein expression and decreased bax protein expression in rats after skin flap surgery, suggesting a potential antiapoptotic role in reducing ischemia-induced damage.

This review discusses the potential of adipose-derived tissue components like nanofat and stem cells for aesthetic rejuvenation, covering their use in hair growth, scar reduction, and more, without reporting new clinical results.

This review highlights that the NLRP3 inflammasome is a promising therapeutic target for cerebral ischemia-reperfusion injury and discusses recent advancements in using natural plant products to modulate this pathway and reduce inflammation.

This study found that compound 3 derived from aza-bicyclo-carboxylic acid may exert a cardioprotective effect by reducing infarction area in myocardial ischemia-reperfusion injury, potentially involving A1-adenosine receptor activation and changes in cAMP levels.

In this study, researchers observed that in a limb ischemia model, vascular transplants preserved for 3 days had better recovery from ischemia-reperfusion injury compared to those preserved for 7 days, with less tissue edema and necrosis.

The study concluded that increasing the GSH concentrations in preservation solutions for follicular units doesn't lessen the oxidative stress during cold ischemia and reperfusion in hair transplantation surgery.

Finasteride may reduce heart damage in rats.

Melatonin may protect inner ear cells from damage by reducing cell death and oxidative stress, potentially treating sudden hearing loss.

In this research, scientists developed a compression therapy model using immobilized mice, successfully analyzing skin without causing injury, and observed increased epidermal thickness and changes in adipocyte volume, with no increase in DNA damage markers.

The researchers reported that introduction of SOX9 in ischemic heart tissues is linked to cardiac fibrosis, marking it as a potential target for future therapeutic strategies.

Testosterone, 4-hydroxyandrostenedione, and finasteride affect blood clotting differently in stressed heart conditions.

This review discusses mesenchymal stromal cell-conditioned medium for various skin conditions and found improvements in wound healing, hair restoration, and more, but emphasizes the need for further research to validate these findings.

In this study, Wnt4 was identified as a key factor in cardiac repair, where its regulation in cardiac fibroblasts improved cardiac function and revascularization following ischemic reperfusion injury.

This review discusses the neuroprotective potential of formononetin, especially for neurological diseases, and reports no clinical results; the authors suggest its promise for developing central nervous system drugs.

This article, a special issue on hair follicle biology and pathology, reports no new research findings.