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Paeoniflorin protects brain cells by involving a specific protein and neurosteroids.

The secretions of mesenchymal stem cells could be used for healing without using the cells themselves.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Changing how mesenchymal stromal cells are grown can improve their healing abilities.

Niosomes are a promising, stable, and cost-effective drug delivery system with potential for improved targeting and safety.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

Some medicinal plants can help heal wounds and may lead to new treatments.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.

Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.

Tiny particles from stem cells help activate hair growth cells and encourage hair growth in mice without being toxic.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.

Conditioned media from mesenchymal stem cell cultures could be a more effective alternative for regenerative therapies, but more research is needed.

Circadian rhythms are crucial for stem cell function and tissue repair, and understanding them may improve aging and regeneration treatments.

PDRN helps repair tissue and improve wound healing with a high safety profile.

Mutations in Gasdermin A3 cause skin inflammation and hair loss by disrupting mitochondria.

Beta-caryophyllene helps improve wound healing in mice, especially in females.

Most low-level light therapy studies did not accurately report how light was measured, affecting treatment reliability.

Microneedle technology has improved drug delivery and patient comfort but needs more research for broader use.

Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.

Finasteride helps reduce heart issues and improves heart function.

Tcf3 helps cells move and heal wounds by controlling lipocalin 2.