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This study found that neoadjuvant chemotherapy followed by interval debulking surgery led to better quality of life and lower perioperative morbidity compared to primary debulking surgery in advanced epithelial ovarian cancer patients with high tumor load.

In this study, researchers presented a protocol for generating planar skin organoids from human induced pluripotent stem cells, which include hair follicles and other skin structures, offering a relevant in vitro model for investigating skin physiology, pathogen interactions, and drug responses.

This study found that conditioned medium from photobiomodulation-irradiated adipose-derived stromal cells enhanced hair growth in a mouse model of hair loss more effectively than non-irradiated medium, suggesting potential for treating alopecia by boosting growth factor secretion.

In this study, researchers developed an innovative wound healing patch combining electrical and chemical components, which effectively guided recovery in animal scald models by promoting collagen deposition and the regeneration of skin structures.

This study found that inhibiting the PI3Kδ enzyme in murine models of cutaneous chronic graft-versus-host disease (cGVHD) reduced skin scores and fibrosis, prevented pathogenic lymphoid structures, and improved survival, suggesting it as a promising therapeutic approach to address the disease's hypoxic pathophysiology.

This research highlights the development of cardiac pacing technologies, focusing on resynchronization and conduction system pacing, with clinicians particularly hopeful about direct left bundle branch pacing.

This review discusses scalp micropigmentation for hair loss and scarring and reports no clinical results; the authors highlight its use as both a standalone and adjunct treatment.

This study explored a cell-free therapy with mesenchymal stem cell paracrine proteins and PEG hydrogels for deep burn treatment and found that the combination significantly enhanced wound healing, reduced scar formation, and promoted skin appendage regeneration in a rabbit model.

This study reported that platelet-rich fibrin (iPRF) therapy may improve scalp health and hair appearance in women, showing beneficial changes in scalp hydration, redness, oiliness, and hair density, thickness, and loss.

This review discusses human epidermal neural crest stem cells (hEPI-NCSC) as candidates for cell-based therapies and drug discovery but reports no new experimental results.

This project by the International Society of Hair Restoration Surgery aims to define best practices in hair restoration surgery but does not report new clinical findings.

This study found that MSN-ceria nanomaterial accelerates cutaneous wound healing in rat models by reducing ROS levels and promoting collagen deposition, leading to improved tissue regeneration without significant scarring.

This study demonstrated that stem cells from the small intestine can differentiate into skin cells and reduce skin damage in irradiated mice, supporting the theory of stem cell plasticity.

This review highlights the potential of microneedles for immunotherapy, emphasizing their ability to enhance immune responses and reduce side effects through precise and stimuli-responsive delivery, especially in tumor treatment, while also noting the limitations and areas for improvement in current systems.

In this preclinical study, researchers developed and evaluated a new non-invasive laser system designed for personalized medical use, showing its potential for chronic disease management and adjunctive fat reduction by offering enhanced treatment precision and adaptability over existing devices.

This study found that incorporating PCL-based nanoscaffolds into liver spheroids enhances their viability and liver-specific biofunctionality, suggesting these scaffolds improve the model's potential for preclinical drug screening by increasing sensitivity to acetaminophen toxicity compared to traditional methods.

This study found that PC 3DP models are reliable preclinical tools that could potentially customize treatment strategies and predict patient prognoses by correlating drug sensitivity profiles with clinical outcomes, though larger patient cohort validation is needed to confirm clinical utility.

Adipose-derived stem cells can be transformed into hair-forming cells using specific extracellular vesicles, offering potential for hair regeneration therapies.

This review examines the role of epidermal stem cells in wound healing, discussing their characteristics and mechanisms, but does not report new clinical results.

Invasomes effectively deliver drugs through the skin and have potential for improved treatments.

This review reports that combining adipose-derived stem cells with decellularized extracellular matrix enhances tissue repair by improving scaffold biological activity and promoting angiogenesis, integration, and functional regeneration across various tissues, while addressing challenges in traditional transplantation methods.

This study found that P144 (Disitertide) significantly reduced collagen deposition and improved muscle organization in a rabbit model of post-radiotherapy fibrosis, suggesting potential antifibrotic effects.

This abstract contains author information and a disclosure regarding the Mohebi Inserter for hair transplantation but provides no new clinical research findings.

This source outlines the scope and content of the Dermatologic Surgery journal, highlighting its focus on comprehensive peer-reviewed information related to various dermatologic surgeries, including cosmetic and reconstructive procedures and skin cancer treatment, as an essential resource for professionals in the field.

This project by the International Society of Hair Restoration Surgery reviews best practices in hair restoration surgery and reports no new research findings.

This study demonstrated that EVs from pluripotent stem cell-derived mesenchymal stem cells improved recovery and function in ischemic lower limbs by enhancing angiogenesis through the ERK/MAPK signaling pathway.

This study argues for "clinical trial re-innovation," highlighting new designs like basket, umbrella, and platform trials that incorporate biomarker technologies to meet the dynamic needs of precision medicine, potentially enabling more effective, patient-specific treatments and overcoming limitations of traditional disease-centered trials.

This study found changes in the PGI2 pathway, especially in gene and protein expression, in diabetic mice, but did not observe PGI2-dependent vasomotor dysfunction.

This article describes newly designed tools that reportedly ease and enhance hair transplantation surgery by improving precision, reducing graft trauma, and monitoring essential conditions.

This study found that phenyl-imidazole sulfonamide derivatives, particularly ISCK03, inhibited c-kit signaling and promoted depigmentation in various experimental settings, suggesting potential use as skin-whitening agents.