24 citations
,
June 2003 in “Journal of Structural Biology” This study suggests that varying intersheet interactions may explain the differences between the two polymorphic forms of macrofibril assembly in Merino wool and hair.
23 citations
,
December 2020 in “Frontiers in Cell and Developmental Biology” This review explores recent insights into how intrinsic gene oscillations and molecular interactions in hair follicle stem cells contribute to their regenerative potential, with potential implications for regenerative medicine, but reports no new clinical results.
56 citations
,
April 2019 in “The Plant Journal” This study found that CNGC 6, CNGC 9, and CNGC 14 are crucial for maintaining calcium oscillations necessary for normal root hair growth in plants, with mutations leading to defects like swelling and bursting.
December 2009 in “Digital Library of Theses and Dissertations (Universidade de São Paulo)” This study found that iontophoresis significantly increased the retention of minoxidil sulfate in hair follicles, potentially improving drug delivery for androgenic alopecia treatment.
February 2026 in “Applied Biosciences” In this study, a computational analysis of promoter regions in human fertility-related genes identified several new candidate regulatory motifs, but these require further experimental validation due to the limitations of being an in silico examination.
1 citations
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January 2022 This study reported that a combination of Myo-inositol and D-chiro-Inositol improved clinical and laboratory parameters in teenage girls with PCOS compared to a placebo.
August 2026 in “Journal of Nanobiotechnology” In testosterone-induced AGA mouse models, this study found that a dual-drug-loaded cationic nanoemulsion of minoxidil and finasteride enhanced follicle-associated retention, supporting hair regeneration while reducing systemic absorption and showing good skin compatibility, indicating a promising approach for androgenetic alopecia treatment.
14 citations
,
September 2012 in “Journal of nanoscience and nanotechnology” In this study, loading niosomes with Oryza sativa bran extract altered their physical properties, suggesting potential for developing formulations aimed at anti-hair loss products.
November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that Imaging Mass Cytometry effectively visualizes multiple biomarkers in alopecia areata, enhancing analysis of immune cell and tissue interactions in hair pathology.
1 citations
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July 2017 in “Microscopy and Microanalysis” In this study using C57BL/6 mice, researchers found that iron oxide nanoparticles permeated skin primarily through hair follicles and sebocytes, with absorption increasing over time.
9 citations
,
October 2025 in “MedComm” This review discusses the development and clinical progression of PROTAC technology for targeted protein degradation, highlighting its potential to address previously "undruggable" targets but reports no new clinical results.
March 2026 in “Materials Today Bio” This study developed a minimally invasive cryo-microneedles array patch (cryo-MAP) technique for transplanting hair follicle organoids, showing successful hair growth and complex skin structure regeneration with over 86% success in 15 days, opening new possibilities in tissue engineering.
477 citations
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March 2004 in “Proceedings of the National Academy of Sciences” This study reports that the DMI3 gene, essential for nodule formation in legume-rhizobial symbiosis, encodes a calcium/calmodulin-dependent protein kinase, highlighting its role in multiple plant symbioses.
July 2026 in “Journal of Ovarian Research” In this review, researchers provided a comprehensive analysis of anti-androgen therapies for polyendocrine metabolic ovarian syndrome (PMOS/PCOS), examining their efficacy and safety while proposing a phenotype-guided management framework and highlighting research gaps, such as long-term cardiovascular safety and predictive biomarkers.
22 citations
,
September 2014 in “JAMA dermatology” This study identified major criteria including ectodermal malformations for diagnosing ichthyosis with confetti, and revealed significant genetic variation in the disease locus within the general population.
29 citations
,
February 2021 in “Cancers” This review discusses the role of ion channels in ovarian cancer progression and chemotherapy resistance, highlighting their potential as targets for diagnosis and treatment, but reports no new clinical results.
1 citations
,
January 2024 in “International journal of molecular sciences” This study investigated the molecular mechanisms of hair follicle morphogenesis in Ordos fine-wool sheep, identifying differential genes related to primary and secondary hair follicles, and providing important insights for improving wool quality and breeding strategies.
15 citations
,
July 2004 in “Journal of morphology” This study analyzes the fine structure and protein distribution in monotreme hairs, finding similarities with other mammals and detailing unique immunocytochemical features in their inner root sheaths.
August 2016 in “Journal of Investigative Dermatology” This study explored the role of nine specific miRNAs in human hair follicles, revealing significant miRNA/mRNA correlations for miR-24, miR-31, and miR-106a and identifying target genes involved in hair biology.
3 citations
,
October 2022 in “Nano Letters” This study found that a microneedle patch using manganese thiophosphite showed greater hair regrowth potential compared to minoxidil, even with less frequent application, for treating androgenetic alopecia.
8 citations
,
March 2017 in “Journal of Mind and Medical Sciences” This article discusses the theoretical perspective of the informational dichotomy of the mind in relation to sexuality and presents no new empirical results; further theoretical exploration is planned.
7 citations
,
October 2018 in “BMC genomics” This study reveals that β-catenin and retinoic acid are key regulators in the gene networks controlling the fate of skin appendages, such as scales and feathers.
December 2025 in “BMC Medical Genomics” This study demonstrated that RNA-seq can effectively expand hair follicle transcriptomic profiling in a multi-center study, offering deeper insights than blood transcriptomics alone.
33 citations
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July 2007 in “Journal of cell science” This study found that knocking out the transactivation domain of Miz1 in mouse keratinocytes disrupted hair follicle orientation, caused irregular pigmentation, and increased keratinocyte proliferation, indicating Miz1's role in hair follicle development and morphogenesis.
This study found that targeting peroxisomal dysfunction with catalytic nanozymes enhanced hair follicle regeneration and outperformed minoxidil in promoting hair growth and maintaining efficacy in immunodeficient mice.
This study found that the FER/MLO signaling module plays a crucial role in calcium oscillations and ROS production in root hair tip growth, with the MLO15 protein regulating these processes and restoring disrupted growth and signaling in fer mutant root hairs.
47 citations
,
July 2014 in “European Journal of Pharmaceutics and Biopharmaceutics” This study concluded that polymeric nanoparticles effectively targeted hair follicles for drug delivery, but the organogel formulation did not enhance their penetration into the hair shaft.
2 citations
,
February 2025 in “Advanced Healthcare Materials” This study developed microfluidics-based 3D microtumors to model minimal residual disease in ovarian cancer, highlighting their alignment with patient-derived MRD and response to a fatty acid oxidation inhibitor.
October 2025 in “Communications Medicine” This study found that using a combination of genotypic and primarily phenotypic reanalysis significantly enhances the accuracy of molecular diagnoses in patients suspected of having monogenic diabetes.
This study found that niosomal aminexil was more clinically effective for hair growth than conventional aminexil solutions, and that niosomes facilitated aminexil penetration through rat skin without propylene glycol.