October 2024 in “Medicina Estética Revista Científica de la Sociedad Española de Medicina Estética (SEME)” This study suggests that follicular unit viability during hair transplantation is best preserved at lower storage temperatures, specifically around 4 °C, and provides insights into optimal cooling practices to enhance transplant success.
36 citations
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October 2014 in “Langmuir” This study concluded that bleach treatment partly transforms the hydrophobic top layer of human hair cuticles into a hydrophilic surface with clustered cysteic acid, visualized at the nano-scale using dynamic Chemical Force Microscopy.
13 citations
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November 2017 in “Neurotoxicity research/Neurotoxicity resarch” This study found that sodium metabisulfite activates sodium channels and increases cellular excitability and excitotoxicity in both cardiomyocyte and neuron models, which exacerbates seizures and neuronal damage in rats.
June 2026 in “Advanced Healthcare Materials” In this study, a taurine-based ionic liquid was developed to effectively penetrate the skin barrier and deliver antioxidants to hair follicles, reducing oxidative stress and promoting hair regrowth in an androgenic alopecia animal model.
June 2026 in “International Journal of Pharmaceutics”
December 2024 in “Problems of Biological Medical and Pharmaceutical Chemistry” This study examined the hair ionomic profiles of first-year RUDN University students and found distinct elemental differences between those from the Moscow region and the Middle East, suggesting these profiles may reflect the geographical and climatic conditions of their previous environments.
May 2024 in “Chemical engineering journal” This study reports that a new minoxidil and epigallocatechin gallate co-loaded ionic liquids system showed superior efficacy in promoting hair regrowth in a mouse model of androgenic alopecia by activating hair follicle stem cells and improving microenvironment conditions, compared to existing minoxidil products.
October 2023 in “Journal of Molecular Liquids” This study demonstrated that imidazole-based ionic liquids, particularly [Emim]DEP, effectively dissolved yak hair keratin, maintaining its structure better than other tested solvents, and also performed well on human hair and goat wool, with consistent performance even after five recycling cycles.
2 citations
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November 2009 in “Korean journal of chemical engineering” This study found that the nonionic surfactant Brij 78 stabilized cationic minoxidil microparticles against aggregation, maintaining their substantivity in the presence of excess anionic surfactant.
January 2025 in “Analytical Methods” This study reports the development of a fluorescent ionic liquid that shows high sensitivity and selectivity for detecting dextran sulfate sodium, with potential applications in clinical diagnostics and environmental monitoring.
January 2025 in “SSRN Electronic Journal” July 2013 in “Pharmaceutical Regulatory Affairs Open Access” Formulation F1 is the best for delivering finasteride effectively.
15 citations
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January 2020 in “RSC advances” In this study, researchers developed a new Supported Ionic Liquid Phase palladium catalyst that showed effectiveness in aminocarbonylation reactions for synthesizing pharmaceutical compounds like CX-546 and a precursor of Finasteride, though results were sensitive to substrate variations and prompted palladium leaching concerns.
February 2025 in “ACS Applied Materials & Interfaces” This study found that a novel choline-based valproic acid ionic liquid significantly enhances transdermal penetration and promotes hair regrowth without causing irritation or toxicity, offering a promising treatment option for alopecia.
November 2023 in “International Journal of Pharmaceutics” This study reported that a novel ionic liquid delivery system combining ferulic acid and finasteride enhanced the solubility, skin permeation, and effectiveness in promoting hair regrowth in androgenetic alopecia mice, suggesting an improved topical treatment approach.
12 citations
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November 2020 in “Pharmacognosy Journal” This study found that 1-butyl-3-methylimidazolium tetrafluoroborate is the optimal ionic liquid solvent for extracting quercetin from Nothopanax scutellarium leaves.
6 citations
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May 2022 in “Journal of Organometallic Chemistry” This study developed a catalytic system using indenyl-molybdenum(II)-bipyridine complexes and ionic liquid solvents to achieve a 95% yield of campholenic aldehyde from α-pinene oxide under mild conditions.
May 2026 in “Waste and Biomass Valorization”
12 citations
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March 2020 in “Journal of Bioactive and Compatible Polymers” This study found that finasteride- and minoxidil-loaded nanoparticles in a gel improved skin permeability and drug retention, suggesting a promising approach for topical alopecia treatment with reduced dosing frequency and side effects.
5 citations
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October 2007 in “PubMed” This study discusses the effects of incorporating various amino acids in hair care products, noting improvements in hair surface properties and color retention when integrated with conditioners.
2 citations
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January 2023 in “BioMed Research International” The researchers reported that a 5% Beta vulgaris L. extract nanogel showed better antialopecic activity in testosterone-induced alopecia in mice compared to a 2.5% concentration.
2 citations
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April 2008 in “Journal of Dispersion Science and Technology” This study observed that including cationic minoxidil particles in a shampoo facilitated notable hair growth promotion despite a negative surface charge after rinsing, likely due to ionic interactions with the skin.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, a chitosan-based minoxidil nanogel was developed and optimized for better scalp retention and targeted follicular delivery, showing sustained drug release over 48 hours and improved drug deposition compared to conventional minoxidil solutions.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study developed a chitosan-based nanogel for minoxidil, showing in vitro sustained drug release and higher deposition compared to conventional solutions, suggesting potential as an effective topical treatment for alopecia.
January 2026 in “MEDS Clinical Medicine” This review highlights emerging evidence that biophysical and metabolic cues, such as oxygen levels and tissue mechanics, significantly influence skin stem cell behavior, which is crucial for developing advanced wound healing therapies beyond traditional infection and inflammation control.
September 2025 in “Голова и шея.” This study examined human hair follicles exposed to different artificial media and found that Dimephosphone solution better preserved the potassium-sodium ion balance, suggesting its potential advantage for short-term graft storage compared to standard saline, which caused significant potassium "washout.
July 2025 in “Pharmaceutics” This review discusses the application of transdermal drug delivery systems for androgenetic alopecia and explores new technologies to enhance drug penetration but reports no clinical results.
December 2023 in “Journal of molecular structure” This study found that hair membrane fluidity is low in the cuticle but high in the cortex and medulla, with treatments like ionic surfactants and oleic acid increasing fluidity in hydrated hair; however, dehydration significantly reduces fluidity throughout the hair.
This study found that nanoparticles developed with minoxidil-loaded thiolated β-cyclodextrins showed improved drug retention on hair surfaces and did not cause skin irritation in rabbits, suggesting potential for topical scalp disease treatment.
August 2023 in “International Journal of Molecular Sciences” In this study, researchers developed a new sodium alginate/chitosan/Zn2+ hydrogel that showed improved physical properties, antibacterial activity, and biocompatibility, and demonstrated enhanced wound healing and skin regeneration in an in vitro model.