Minoxidil-Induced Cardiac Hypertrophy in Guinea Pigs

The study found that minoxidil, a drug used for hair loss treatment, can cause cardiac hypertrophy in guinea pigs, indicating potential harm to the heart. The drug can lead to changes in heart muscle properties, weight, and composition, and caution is advised when using it in patients with pre-existing cardiovascular conditions. Higher doses of minoxidil can lead to greater increases in heart weight, and the condition developed gradually with low mortality rates. The drug may have potential cardiovascular side effects, and long-term use can cause eccentric left ventricular hypertrophy due to volume overload.