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    Glossary Cardiac Hypertrophy

    thickening of heart muscle due to increased workload

    Cardiac Hypertrophy, also known as Myocardial Hypertrophy, is the thickening of the heart muscle, specifically the myocardium. This condition can result from increased workload on the heart due to high blood pressure or other cardiovascular diseases, leading to an enlarged heart that may struggle to pump blood efficiently. While it can be a compensatory response to increased demand, prolonged hypertrophy can lead to heart failure and other complications.

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    1. Antiandrogenic Therapy With Finasteride Attenuates Cardiac Hypertrophy and Left Ventricular Dysfunction Circulation · 2015 · 56 citations
    2. Maternal androgen excess induces cardiac hypertrophy and left ventricular dysfunction in female mice offspring Cardiovascular Research · 2019 · 21 citations
    3. Maternal androgen excess inhibits fetal cardiomyocytes proliferation through RB-mediated cell cycle arrest and induces cardiac hypertrophy in adulthood Journal of Endocrinological Investigation · 2023 · 2 citations
    4. Targeting cardiac hypertrophy through a nuclear co‐repressor EMBO molecular medicine · 2019 · 3 citations
    5. Gender Differences in Cardiac Hypertrophy Journal of Cardiovascular Translational Research · 2020 · 27 citations
    6. Abstract 153: Inhibition of the 5-a-reductase Reduces Cardiac Hypertrophy and Improves Cardiac Function Circulation Research · 2013
    7. Testosterone, cytochrome P450, and cardiac hypertrophy The FASEB Journal · 2002 · 155 citations
    8. Development of Autoimmune Hair Loss Disease Alopecia Areata Is Associated with Cardiac Dysfunction in C3H/HeJ Mice PLOS ONE · 2013 · 18 citations
    9. Finasteride promotes worsening of the cardiac deleterious effects of nandrolone decanoate and protects against genotoxic and cytotoxic damage Figshare · 2020
    10. Male sex hormone and reduced plakoglobin jointly impair atrial conduction and cardiac sodium currents bioRxiv (Cold Spring Harbor Laboratory) · 2022
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    1. The Biggest Concern That I Have For Oral Minoxidil: Cardiac Hypertrophy Reddit · 11 Jun 2023
    2. I experienced severe cardiac and renal side effects with only 1.25 mg of minoxidil Reddit · 29 Aug 2026
    3. The dose dependent nature of the cardiac effects RU58841 Reddit · 3 Jan 2026
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