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Glossary Left Ventricular Hypertrophy

thickening of the heart's left ventricle muscle wall

Left Ventricular Hypertrophy (LVH) is a condition where the muscle wall of the heart's left ventricle thickens. This thickening can result from high blood pressure or other heart conditions, and it can lead to reduced heart efficiency and increased risk of cardiovascular events.

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Research

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research Antiandrogenic Therapy With Finasteride Attenuates Cardiac Hypertrophy and Left Ventricular Dysfunction

56 citations , January 2015 in “Circulation”

This study found that finasteride treatment improved cardiac function and reduced heart failure progression in mice, suggesting it could be a potential therapy for pathological cardiac hypertrophy and dysfunction.

research Maternal androgen excess induces cardiac hypertrophy and left ventricular dysfunction in female mice offspring

21 citations , July 2019 in “Cardiovascular Research”

This study found that prenatal exposure to androgens caused long-lasting heart remodeling and left ventricular hypertrophy in female mice offspring, suggesting potential cardiac risks for daughters of mothers with PCOS.

research Dihydrotestosterone—a culprit in left ventricular hypertrophy

4 citations , January 2012 in “International Journal of Cardiology”

Dihydrotestosterone (DHT) worsens heart enlargement, and blocking it may help prevent heart issues.

research Improving translational research in sex-specific effects of comorbidities and risk factors in ischaemic heart disease and cardioprotection: position paper and recommendations of the ESC Working Group on Cellular Biology of the Heart

47 citations , May 2020 in “Cardiovascular Research”

This review explores how sex differences influence the pathophysiology, incidence, and treatment outcomes of ischaemic heart disease, and emphasizes the need for more sex-specific research.

research Severity of Alopecia Predicts Coronary Changes and Arterial Stiffness in Untreated Hypertensive Men

5 citations , July 2016 in “Journal of Clinical Hypertension”

This study found that hypertensive patients with severe androgenic alopecia exhibited impaired coronary microcirculation, suggesting they may face increased cardiovascular risk.

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community Extreme caution: my experience using Ru58841 only once

in Treatment 10 upvotes 1 year ago

An 18-year-old experienced severe side effects, including heart palpitations and high blood pressure, after using RU58841 once, leading to a referral to cardiology for suspected left ventricular hypertrophy. The user regrets using RU58841 and seeks advice on recovery, while others suggest preexisting conditions or genetic predispositions may be factors.

community The Biggest Concern That I Have For Oral Minoxidil: Cardiac Hypertrophy

26 upvotes 3 years ago

Oral minoxidil can cause serious heart issues like cardiac hypertrophy and arrhythmias, prompting some users to reduce dosage or switch to topical treatments. Despite significant hair regrowth, side effects such as shortness of breath and chest pains are common concerns.

community Has anyone ever tried nandrolone to regrow hair?

4 upvotes 1 year ago

Nandrolone is discussed as a potential treatment for hair regrowth, with some users noting its effectiveness but also its risks, such as organ damage and cardiovascular issues. It is suggested not to be used with finasteride, and some users are experimenting with alternative hormone therapies for hair thickening.

community Rethinking DHT and Hair Loss: Are We Targeting the Wrong Enemy?

in Research/Science 1 year ago

Blocking DHT is not a complete solution for hair loss; instead, altering the scalp's response to DHT may be more effective. Topical finasteride and minoxidil are current treatments, but future approaches may involve bioengineering, gene therapy, and inflammation control.

community How is this even possible that there is no cure till now

in Technology 155 upvotes 5 months ago

There is no permanent cure for hair loss; treatments like finasteride, minoxidil, and hair transplants require ongoing use and are not universally effective. Genetic complexity and financial incentives for ongoing treatments hinder the development of a definitive cure.

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