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    Glossary Pellagra

    disease from niacin deficiency causing dermatitis, diarrhea, dementia

    Pellagra is a disease caused by a deficiency of niacin (vitamin B3) or its precursor tryptophan. It is characterized by the "three Ds": dermatitis, diarrhea, and dementia, and if left untreated, it can be fatal. This condition often arises in populations with diets heavily reliant on corn, which lacks adequate niacin and tryptophan unless properly processed.

    Research

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      research Pellagra and anorexia nervosa: a case report

      8 citations , September 2019 in “Eating and Weight Disorders - Studies on Anorexia, Bulimia and Obesity”
      This case report illustrates that pellagra can develop in patients with anorexia nervosa without typical signs of severe malnutrition, responding rapidly to nicotinamide and tryptophan therapy.

      research The photosensitive patient: could it be pellagra?

      2 citations , May 2011 in “British Journal of Dermatology”
      This review discusses the diagnosis and treatment of pellagra, emphasizing the importance of evaluating serum niacin levels in photosensitive patients with certain risk factors, and reports no new clinical results.

      research Pellagrous dermatitis: a forgotten entity

      October 2019 in “Postgraduate Medical Journal”
      This case report describes a patient with pellagrous dermatitis related to chronic alcoholism, whose symptoms resolved within two weeks following treatment with nicotinamide, vitamin B12, and thiamine.

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