Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This paper reviews the development of transdermal drug delivery systems for skin diseases, from first to fourth generation, and highlights ongoing challenges and the importance of clinical trials, but provides no new clinical results.

This study highlights the versatility and potential of injectable hydrogel nanocomposites in biomedical research, emphasizing their roles in controlled drug delivery, tissue regeneration, and treatment of various conditions, such as cardiac issues, joint diseases, and bone regeneration.

This study introduced a new spectrofluorometric method using a synthesized organic fluorophore to effectively analyze darolutamide and thalidomide in pharmaceutical preparations and biofluids.

This review explores the applications of phytonutrient-based biosensors in micro-electrochemical systems and reports no new experimental findings, emphasizing the potential and challenges of this innovative approach.

This review highlights the potential of self-powered nanogenerators in revolutionizing biomedical devices by using biomechanical or environmental energy, focusing on applications like regenerative hair growth, drug release patches, and electronic skin while evaluating challenges such as energy efficiency and biocompatibility.

This review analyzes the role of silver nanoparticles in wound healing, highlighting their antimicrobial, anti-inflammatory, and tissue-regenerating properties, and emphasizes the need for further research to optimize formulations and ensure safety.

This study developed a closed-loop system for emergency wound care that monitors infection in real-time using biomarkers and delivers amikacin-loaded liposomes for treatment, integrating a conductive hydrogel for environmental protection and antibacterial benefits.

This review article summarizes recent advancements in biomimetic scaffolds, highlighting their promise in tissue engineering and personalized medicine, particularly for skin and musculoskeletal system regeneration, while emphasizing the need for more extensive research to ensure their safety for human use.

This review highlights recent developments in nanovesicular carriers for enhancing molecule delivery into and across the skin, focusing on the design and evolution of phospholipid and non-phospholipid systems used in cosmetics and treating various skin conditions.

This study found that a novel shampoo formulation effectively delivers caffeine to hair follicles, with 8–9% of absorbed caffeine reaching the follicles, suggesting it may support hair retention by enhancing antioxidant activity.

In this study, researchers developed gellan gum hydrogels functionalized with biomimetic peptides that create a supportive microenvironment for human dermal papilla cells, enhancing their hair-inductive capacity and ability to mimic hair morphogenesis-like events in vitro.

This study found that paracellular transport significantly contributes to the intestinal permeability of minoxidil, suggesting its limited suitability as a Biopharmaceutics Classification System reference drug due to potential variability.

This study observed that the Pilogics Hairegen device increased total hair count by 23.2% and terminal hair count by 21.1% in 289 patients with androgenetic alopecia after approximately 20 weeks of use, with no adverse effects reported.

This review categorizes contractile hydrogels by their contraction mechanisms and explores their role in advanced wound management, emphasizing mechanical and biochemical signaling in healing, but also notes challenges like force transmission and clinical applicability.

This review outlines the design and engineering of multifunctional hydrogels, emphasizing their evolving biomedical applications, notably in controlled drug delivery, tissue support, and disease management, and discusses their potential for clinical translation.

This study found that TSG-enriched Polygonum multiflorum extract, optimized through microwave-assisted and chromatographic methods, promotes hair regrowth in a mouse model of androgenetic alopecia via 5α-reductase inhibition and Wnt/β-catenin pathway activation, suggesting its potential as a natural treatment.

This review discusses recent advancements in bone tissue engineering, emphasizing a shift from passive to smart responsive antibacterial strategies to prevent implant-associated infections, and highlights AI's role in optimizing bone scaffold design for personalized, infection-free implants.

This study found that radiofrequency microneedling significantly enhanced the absorption of topical triamcinolone acetonide, with insertion depth being more influential than RF energy levels.

This review summarizes the composition, bioactive functions, and potential industrial applications of rice bran polysaccharides, focusing on how extraction methods and modifications impact their biological activities.

This study investigated the secretome of adipose mesenchymal stem cells and fibroblasts used in skin care products, finding 16 therapeutic pathways involving numerous signaling mechanisms, which may offer skin benefits through anti-inflammatory and regenerative effects.

This review discusses therapeutic deep eutectic solvents as promising "green" solutions for enhancing drug solubility and delivery through the skin, reporting no new clinical results and highlighting future research directions.

This study establishes a robust analytical method using mass spectrometry to comprehensively identify 170 chemical compounds in Xiaoban Kangfu capsules for enhanced quality control.

This review highlights how nanotechnology enhances CRISPR-Cas9's potential for cancer treatment by improving delivery and stability, addressing key challenges like immunogenicity and delivery inefficiencies, and discusses recent advancements in stimuli-responsive nanoplatforms for precise genome editing.

This study reported that abietic acid, derived from pine rosin, showed antimicrobial effects and reduced biofilm biomass in laboratory tests against microorganisms like Staphylococcus aureus and Candida albicans, suggesting potential further applications for skin infections.

This paper reviews advancements in 3D human skin models using bioprinting, organoid, and organ-on-a-chip technologies, noting improvements in physiological realism through vascularization and multi-omics data, but also highlighting challenges such as cost and lack of standardization that hinder clinical adoption.

This review highlights that post-oncologic skin suffers from several impairments following cancer treatments, and dermocosmetic strategies, particularly those involving nanocarriers, can enhance the efficacy and stability of antioxidants, thereby aiding skin regeneration and improving quality of life.

This study developed a method using UHPLC-MS/MS and MSPE to detect trace amounts of sex hormones in cosmetics, finding progestins and estrogens in some products, and performed a preliminary safety evaluation for residual progesterone in hair loss prevention cosmetics.

Shrimp extracts may help heal burns and fight bacteria.

This review article identifies a need for standardized guidelines in using photobiomodulation therapy for spinal cord injury repair, emphasizing that current inconsistencies in therapy parameters may hinder optimal outcomes and limit clinical trials.