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This study found that oral contraceptives effectively suppressed hyperandrogenemia in most patients with hyperandrogenic-insulin-resistant acanthosis nigricans syndrome, though GnRH-a therapy was beneficial for those not responding initially.

This study demonstrated that supplementing aged mice with pro-IGF-II improved muscle regeneration by enhancing satellite cell proliferation and reducing adipogenesis, suggesting potential benefits for treating muscle injuries in elderly individuals.

This study concluded that a 3% IGF-1 liposomal gel improved hair thickness and growth in hamsters without inducing significant hepatotoxicity or myelotoxicity, suggesting its potential as a safe hair-loss treatment.

In this pilot study, patients with atrophic acne scars experienced clinical improvements and high satisfaction after receiving three biweekly microinfusions of human insulin into their skin.

This study used Mendelian randomization analysis to find a significant causal relationship between high fasting insulin levels and androgenetic alopecia, while identifying potential core genes and metabolic pathways that could mediate this link.

A woman with type 2 diabetes developed alopecia areata, suggesting a link between the two autoimmune conditions.

This study suggests that mutations in exon 10 of the POC1A gene may be linked to a distinct clinical condition characterized by extreme insulin resistance and short stature, differing from SOFT syndrome.

This study found that women with polycystic ovary syndrome have higher triglyceride and fasting glucose levels in obese individuals and higher total cholesterol levels in non-obese individuals compared to healthy women.

2h-ICPR can help screen for insulin antibodies in type 2 diabetes patients.

This review found that insulin-chitosan formulations, such as gels and dressings, show promise in wound healing through anti-inflammatory and antimicrobial effects, although most evidence is from preclinical studies and further research is needed to understand mechanisms.

This study reports a case of a patient with neuromyelitis optica spectrum disorders treated with eculizumab who developed fatal sepsis after insulin resistance emerged.

The study found that metformin alone most effectively reduced insulin resistance in Iraqi women with PCOS, but combining metformin with finasteride produced greater improvements in insulin sensitivity markers.

This study found that among male medical students in Saudi Arabia, skin tags, acanthosis nigricans, and acne were common dermatological symptoms potentially linked to insulin resistance, and waist circumference was a significant indicator.

This case report describes a pediatric patient with diabetes mellitus type 1 who uniquely also developed membranous glomerulonephritis and alopecia areata, highlighting a rare association of these autoimmune conditions.

In this case report, a novel heterozygous mutation in the insulin receptor gene was identified in an adolescent girl with type A insulin resistance syndrome, characterized by excessive hair growth and skin changes, and her mother.

The Accu-Chek FlexLink Plus and Accu-Chek LinkAssist Plus make insulin pump use safer, simpler, and more comfortable.

This review discusses various syndromes of severe insulin resistance, their biochemical and clinical features, and potential therapeutic options, but it reports no new clinical results.

This study found that four days of simulated night shift work in healthy adults reduced insulin sensitivity, suggesting a potential increased risk of type 2 diabetes.

This study demonstrated that a novel synthetic amyloid template accelerates the deposition of insulin monomers into amyloid fibrils without a lag time, potentially aiding in vitro screening of amyloid deposition inhibitors.

This study found that an increased calcium/magnesium ratio in hair and lower chromium concentration were associated with higher insulin resistance in Korean adult males.

This study found that testosterone enhances insulin secretion in human pancreatic islets by being converted into DHT and E2, processes that are necessary for this effect.

This review discusses the various aspects of insulin resistance and highlights its potential evolutionary benefits, reporting no new experimental findings.

In this case study, a man with Werner syndrome and diabetes saw improved glycemic control and insulin resistance with dapagliflozin, suggesting its potential usefulness for managing diabetes in similar patients.

In this quasi-experimental study, a 12-week intermittent fasting regimen significantly improved insulin sensitivity and reduced HbA1c levels in overweight South Asian adults with prediabetes, suggesting a practical lifestyle strategy to potentially delay the onset of type 2 diabetes.

This paper reports three cases of hair transplantation using Feily's method, which showed unusual long-lasting dark areas on the scalp, suggesting more than 24 hours of caution might be needed to prevent necrosis.

This study found that testosterone enhances glucose-stimulated insulin secretion in male and female human islets through its conversion to DHT and E2, a process disrupted by 5α-reductase and aromatase inhibitors.

This study found that testosterone enhances glucose-stimulated insulin secretion in male and female human islets, requiring conversion to DHT and E2 via SRD5A1 and aromatase.

This study found that scalp hair from individuals with non-insulin dependent diabetes mellitus had significantly different contents of zinc, copper, lead, cadmium, and aluminum compared to controls.

This study found that women with PCOS who had a higher serum estrone-to-estradiol ratio were more likely to exhibit higher fasting insulin and postprandial glucose levels, even after adjusting for BMI and waist-to-hip ratio.

This case report describes the first instance of juvenile hemochromatosis type 2A associated with secondary hypothyroidism, linked to a novel mutation in the HJV gene.