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PDGF-BB helps young melanocytes grow but stops mature ones from growing, and it makes melanocytes more specialized.

The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.

Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.

The hypothesis suggests that PCOS may start early in life due to genetic and environmental factors, influencing future reproductive and metabolic problems.

Antioxidants and growth factors may help treat hair loss when combined with LED and Laser therapy.

Skin problems in the elderly are unique and may indicate other diseases, involving changes in skin, hair, nails, and increased cancer risk.

Adult stem cells with Tp63 can form hair and skin cells when placed in new skin, showing they have hidden abilities for skin repair.

5α-reductase inhibitors help treat disorders caused by DHT and have potential for future therapies.

Maintaining DNA integrity in stem cells is crucial to prevent aging and cancer.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Hair loss requires customized treatments based on its various causes and types.

Hormonal treatments, including birth control and antiandrogens, can effectively treat acne in women.

Old people have less hair because their hair follicles don't regenerate as well, not because of fewer stem cells, and a protein called follistatin might help reactivate hair growth.

Most drugs fail to reach the market, but understanding their properties and using strategies like early toxicity tests and drug repurposing can help advance their development.

PCOS is a hormonal disorder causing symptoms like irregular periods and acne, and increases the risk of diabetes and heart disease.

Genetic defects and UV radiation cause skin damage and aging.

Environmental factors can cause mutations in skin proteins, leading to skin disorders.

PBX1 helps reduce aging and cell death in hair follicle stem cells by decreasing DNA damage, not by improving DNA repair.

Skin bacteria, specifically Streptococcus and Staphylococcus, help in hair regrowth after skin injury and speed up wound healing.

Skin aging is a complex process influenced by various factors, leading to wrinkles and sagging, and should be considered a disease due to its health impacts.

Understanding how different body systems interact can improve how we prevent or treat frailty in aging.

The environment around the time of conception can change the VTRNA2-1 gene in a way that lasts for years and may affect disease risk.

Hormonal male contraception is effective and could be market-ready, but more research is needed to ensure safety for all ethnic groups.

Human hair follicle stem cells can be turned into red blood cells.

Aging changes hair stem cells and their environment, leading to gray hair and hair thinning, but understanding these changes could help develop treatments for hair regeneration.

Stress in hair follicle stem cells causes inflammation in a chronic skin condition through a specific immune response pathway.

Gene therapy shows promise for healing chronic wounds but needs more research to overcome challenges.

Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.

Cancer can hijack the body's cell repair system to promote tumor growth, and targeting this process may improve cancer treatments.

The Wnt/β-catenin pathway can activate melanocyte stem cells and may help regenerate hair follicles.