October 2020 in “International Journal of Research in Dermatology” In this study, adding platelet-rich plasma to minoxidil and finasteride treatment for patterned hair loss improved hair outcomes with minimal side effects compared to using minoxidil and finasteride alone.
109 citations
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April 1998 in “Journal of Investigative Dermatology” This study found that recombinant human HGF/SF injections altered hair follicle growth cycles and mildly promoted hair elongation in mice, depending on their hair cycle stage.
48 citations
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April 2013 in “Expert Opinion on Investigational Drugs” This article reviews emerging treatments for androgenetic alopecia, including topical 5-alpha-reductase inhibitors and prostaglandin modulators, but reports no clinical results and calls for further efficacy evidence, especially for PRP.
16 citations
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April 1998 in “Journal of Investigative Dermatology” ACTH promotes hair growth in mink, but α-MSH does not.
9 citations
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October 1957 in “A M A Archives of Dermatology” In this study, carotene injected into the skin was converted into vitamin A by sebaceous gland cells, where it was not normally detectable.
7 citations
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January 2015 in “International Journal of Trichology” This case report describes a woman who experienced frontal edema after topical minoxidil application following mesotherapy, noting that excessive absorption of minoxidil may cause localized vasodilatory side effects.
1 citations
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March 2023 in “Pharmaceutics” This study found that PBMCsec has anti-fibrotic effects on mouse and human skin scars by regulating pro-fibrotic gene expression and inhibiting myofibroblast differentiation and elastic fiber breakdown.
July 2026 in “Clinical Case Reports” This single-patient case study reported promising results for severe, corticosteroid-resistant alopecia areata, with treatment using exosomes derived from mesenchymal stromal cells leading to almost complete hair regrowth in 12 weeks and favorable changes in inflammatory markers, suggesting potential for further investigation.
May 2026 in “Journal of Asia Pacific Aesthetic Sciences” This case report highlights significant hair regrowth in a Malaysian woman with localized alopecia areata after intralesional triamcinolone acetonide treatment at a concentration of 5 mg/mL.
January 2026 in “Ciencia Latina Revista Científica Multidisciplinar” In this case study, a 14-year-old boy with treatment-resistant diffuse alopecia areata achieved complete hair regrowth following three monthly sessions of microneedling combined with injections of triamcinolone, dutasteride, and synthetic exosomes, suggesting that exosome-based therapy could be a promising alternative for managing refractory autoimmune alopecia.
January 2026 in “International Society of Hair Restoration Surgery” This study reports that a novel multimodal approach, combining tattoo machine–assisted drug delivery of hair loss treatments with oral and topical medications, may enhance hair density and thickness in androgenetic alopecia patients, though larger controlled studies are needed to confirm these early findings.
April 2025 in “Health Science Reports” PRP treatment improved skin pigmentation and appearance in facial lichen planus pigmentosus.
This study summarizes the therapeutic use of mesotherapy using vitamins, trace elements, and stem cell extracts for treating alopecia, noting its effectiveness in addressing both androgenetic alopecia and telogen effluvium as demonstrated in various clinical trials.
A 72-year-old man was diagnosed with a rare skin form of Rosai-Dorfman disease after years of misdiagnosis.
January 2019 in “Proceedings for Annual Meeting of The Japanese Pharmacological Society” In this study, injecting Nε-(carboxymethyl) lysine into skin tissue weakened hair shaft and follicle formation, likely by inhibiting cell proliferation and migration needed for hair follicle morphogenesis.
April 2016 in “Dermatología Revista Mexicana” This experimental study found no significant difference in hair follicle characteristics after short-term treatment with autologous platelet-rich plasma in individuals with androgenic alopecia compared to placebo.
231 citations
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October 1999 in “Journal of Clinical Investigation” This study found that administering an adenovirus vector to increase Sonic hedgehog gene expression in mouse skin accelerated the transition of hair follicles into the growth phase, promoting hair growth.
86 citations
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August 2021 in “Polymers” This review discusses the potential of microneedles to enhance transdermal drug delivery by expanding the range of deliverable drugs, highlighting fabrication methods, material choices, and applications, but notes existing challenges with sustained delivery, cost-effectiveness, and large-scale production.
68 citations
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December 1983 in “British Journal of Dermatology” This study found HLA and beta 2-microglobulin antigens in various skin structures, with specific localization patterns in keratinocytes and hair follicle components, but not in eccrine or apocrine glands.
36 citations
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January 2015 in “Clinical and Translational Allergy” This review discusses allergic reactions to pollen in dogs, cats, and horses and suggests that these animals' spontaneous allergies could serve as models for translational clinical studies applicable to human allergies.
22 citations
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July 2019 in “PLOS ONE” This study found that lymphatic vessels promote hair follicle growth in mice and may represent new therapeutic targets for hair loss conditions.
22 citations
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September 1986 in “Journal of Investigative Dermatology” This study found that low-dose topical alpha-terthienyl combined with UVA radiation can induce cutaneous photosensitization in guinea pigs, suggesting a possible photochemotherapy approach for skin diseases like psoriasis.
18 citations
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June 2020 in “Dermatologic Therapy” In this study, FCO2 laser treatment showed significantly better improvement for alopecia areata compared to traditional intralesional corticosteroid injections, with no serious side effects or relapse observed.
3 citations
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December 2018 in “International Journal of Biomedicine” This study found that treating androgenetic alopecia with platelet rich plasma increased hair density and diameter while decreasing the proportion of telogen and vellus hairs.
August 2025 in “Stem Cell Reviews and Reports” This study demonstrated that adipose derived stem cells nanovesicles enhanced hair growth and reduced sebum secretion in androgenetic alopecia, showing effects comparable to minoxidil in laboratory and mouse models.
This review discusses the effectiveness of adipose-derived stem cells in treating alopecia, reporting on various clinical studies but presenting no new clinical results.
This study found that follicular unit extraction can be safely performed without bupivacaine and nerve blocks, using lignocaine with adrenaline as an effective anesthetic for patients with certain grades of androgenetic alopecia.
April 2021 in “Journal of Investigative Dermatology” New inhibitors may help treat hair loss by promoting fat cell growth in the skin.
January 2021 in “Journal of the European Academy of Dermatology and Venereology” PrEP doesn't increase STI risk in high-risk men, anti-androgen drugs may lower ICU admission for male COVID-19 patients, a 3-point injection is better for crow's feet, and the 'Geriatric-8' tool could help assess frailty in older skin cancer patients.
December 2019 in “Pubvet” This article discusses the diagnosis and management of allergic dermatoses in dogs, focusing on clinical diagnosis, complementary tests, and various treatment strategies, but it reports no new results.