Editor's Picks January 2021

    January 2021 in “ Journal of the European Academy of Dermatology and Venereology ”
    Image of study
    TLDR PrEP doesn't increase STI risk in high-risk men, anti-androgen drugs may lower ICU admission for male COVID-19 patients, a 3-point injection is better for crow's feet, and the 'Geriatric-8' tool could help assess frailty in older skin cancer patients.
    In January 2021, several studies were highlighted in the field of dermatology and related health issues. One study by Colas et al. involving 92 high-risk MSM (men who have sex with men) participants found that pre-exposure prophylaxis (PrEP) did not increase the risk of acquiring new sexually transmitted infections (STIs), emphasizing the need for regular STI screening and safe sex practices in this population. Another study involving 77 hospitalized male COVID-19 patients suggested that anti-androgen medications, such as 5-alpha-reductase inhibitors (5ARis), could reduce the risk of ICU admission, particularly in older individuals with cardiovascular comorbidities. This study also indicated that genetic variations in the androgen receptor gene might predict COVID-19 disease severity. A separate clinical trial with 48 subjects compared two injection techniques of incobotulinumtoxinA for treating crow's feet and found that a 3-point intramuscular injection was more effective and longer-lasting than a 6-point intradermal injection, with less pain and bruising. Lastly, a modified Delphi study on frailty screening in dermatology-oncology practice identified the 'Geriatric-8' (G8) as a potentially suitable tool for assessing frailty in older patients with skin cancer, though further research is needed.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 1000+ results

      community Breezula phase 3 results said to be released next month

      in Product  25 upvotes 3 weeks ago
      Breezula's phase 3 results are expected soon, with discussions on the effectiveness of androgen receptor antagonists like spironolactone and the potential of GT20029. Users express skepticism about new treatments and discuss the complexities of male pattern baldness, often relying on finasteride despite its side effects.
      [object Object]

      community Trying to understand finasteride side effects and post finasteride syndrome

      in Finasteride/Dutasteride  73 upvotes 4 years ago
      The conversation discusses the side effects of finasteride, including low libido and erectile dysfunction, and the possibility of these effects being permanent, known as post-finasteride syndrome (PFS). Some users report personal experiences with PFS and debate whether the condition is real, with varying opinions on the reversibility of side effects and the role of individual biology.

      community Female, 30, PCOS diagnosis, MPB Norwood 2. Endo refuses to give anything other than Spironolactone. Feel like I’m at my wit’s end here.

      in Female  55 upvotes 1 year ago
      A 30-year-old female with PCOS and male pattern baldness is frustrated with her endocrinologist's recommendation of only Spironolactone and minoxidil, feeling that dutasteride, finasteride, and progesterone would be more effective. Other users suggest various online sources for treatments, warn against self-medicating due to potential risks, and recommend seeking a specialized endocrinologist or considering additional treatments like Inositol, Berberine, and dermaneedling.
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  828 upvotes 5 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community How to know if shedding is from tren or minoxidil?

      in Minoxidil  5 upvotes 9 months ago
      The user started using trenbolone and minoxidil simultaneously and experienced increased hair shedding, unsure which is causing it. Replies suggest both drugs could cause hair loss, with one advising to stop trenbolone to protect hair and another indicating minoxidil is unlikely the cause due to the timing.

    Similar Research

    5 / 1000+ results