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Free fatty acids in sebum boost skin's defense against acne by increasing antimicrobial peptides.

DHEA affects various tissues by interacting with multiple receptors and can be converted into sex hormones.

Colchicine might help treat different skin diseases, but more research is needed to confirm its effectiveness and safe dosage.

The right cells and signals can potentially lead to scarless wound healing, with a mix of natural and external wound healing controllers possibly being the best way to achieve this.

TRPV4 helps cells repair tissue and reduce scarring by controlling calcium levels.

Ginseng, especially its component ginsenosides, can promote hair growth, reduce hair loss, and potentially treat conditions like alopecia by affecting cell pathways and cytokines.

Etanercept, a psoriasis treatment, caused hair loss in a patient.

Transplanted hair follicle stem cells can heal damaged rat intestines.

Lupus is a complex disease that requires personalized treatment because it varies greatly between individuals.

KLF4 is important for maintaining stem cells and has potential in cancer treatment and wound healing.

TNF-alpha inhibitors can cause various immune-related skin issues.

Some wound-healing cells can turn into fat cells around new hair growth in mice.

Platelet lysate is a promising, cost-effective option for regenerative medicine with potential clinical applications.

Noncoding dsRNA boosts hair growth by activating TLR3 and increasing retinoic acid.

The document concludes that careful design of genetic fate mapping experiments is crucial for accurate cell lineage tracing in mice.

Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.

Prolactin may play a significant role in skin and hair health and could be a target for treating skin and hair disorders.

The document concludes that alopecia has significant social and psychological effects, leading to a market for hair loss treatments.

Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.

Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Hair color production is closely linked to the active growth phase of hair in mice and may also influence hair growth itself.

Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.

MicroRNAs are important for skin health and could be targets for new skin disorder treatments.

Apigenin, found in plants and vegetables, has many health benefits, including anti-inflammatory, antioxidant, and anticancer effects.

The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Certain immune cells contribute to severe hair loss in chronic alopecia areata, with Th17 cells possibly having a bigger impact than cytotoxic T cells.