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Rosuvastatin improves lipid levels, reduces inflammation, but worsens insulin sensitivity in men with early-onset hair loss.

The new rodent model successfully mimics non-lean human PCOS symptoms.

Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.

Removing myelin protein zero-like 3 in mice leads to better metabolism and resistance to obesity.

Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.

Surgery to lower high testosterone in postmenopausal women with certain ovarian tumors doesn't significantly affect their metabolism.

Early treatment and weight management are important for teenagers with PCOS to reduce symptoms and long-term health risks.

Epilepsy and certain epilepsy drugs can lead to reproductive problems in women, but changing medication might improve these issues.

Diet and supplements can significantly affect acne, with some foods and nutrients reducing and others worsening it.

5-alpha reductase inhibitors can cause sexual, neurologic, endocrine, and cardiovascular side effects, but these are rare and usually stop after ending treatment.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Eating high-glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.

Rosiglitazone may be better than metformin for insulin resistance in PCOS, but more research is needed on certain biomarkers.

Patients with acne vulgaris have lower serum irisin levels.

Insulin resistance is common in PCOS patients and linked to obesity and increased cardiovascular risk.

Blocking DGAT1 reduces oil gland size in mice and dogs, but only mice experience hair loss.

Metformin helps manage diabetes, PCOS, and weight in kids but needs more research for long-term safety.

Oxidative stress worsens PCOS by damaging cells and disrupting metabolism, suggesting antioxidant treatments might help.

Testosterone and finasteride raise insulin and zinc, lower chromium in male rats.

N-acetylcysteine was more effective and had fewer side effects than metformin for improving insulin resistance in women with PCOS.

Certain skin conditions in women are linked to higher risks of metabolic syndrome and type 2 diabetes due to hormone imbalances.

Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.

Long-term use of finasteride and dutasteride can cause serious health issues like diabetes and liver problems.

Low selenium levels can extend lifespan but worsen health issues.

The document concludes that PCOS in adolescents is complex and requires comprehensive care to manage its symptoms and associated health risks.

Myo-inositol may be more effective than metformin for inducing ovulation in women with PCOS.

Exposure to fatty acids significantly increased androgen levels in female dogs, suggesting a link to conditions like insulin resistance and PCOS.

Lifestyle changes and weight loss are key for treating PCOS-related metabolic issues and infertility, with various medications available for specific symptoms.

Proper nutrition can help manage PCOS symptoms and improve overall health.

MicroRNAs could be key biomarkers and therapeutic targets for PCOS.