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The 2023 guideline for PCOS suggests using updated diagnostic criteria, assessing related health risks, and recommends lifestyle changes and specific treatments for symptoms and fertility issues.

The 2023 guideline advises a detailed approach for PCOS, focusing on early detection, lifestyle and medical treatments, and managing health risks.

Baricitinib and its combination with lonafarnib improve fat cell formation in certain genetic disorders.

Myotonic Dystrophy may age cells faster, and drugs that target aging could be potential treatments.

There is no causal relationship between androgenetic alopecia and serum uric acid.

The conclusion is that obesity should be managed with a slow, balanced approach to diet and exercise, with medication and surgery as additional options, and education and access to care are important.

Selenium is essential for health, but too much or too little can cause problems; blood selenium levels are a good measure of intake.

A woman's rare benign tumor that released both cortisol and testosterone was successfully removed, improving her health.

Long COVID causes a wide range of long-lasting symptoms that change over time and are hard to diagnose and treat.

Lower hair copper and copper-to-zinc ratio are linked to more severe coronary artery disease.

Adult acne is often related to hormonal disorders, especially in women, and may need long-term treatment involving specialists.

Hormonal changes and conditions like polycystic ovarian syndrome are major causes of adult acne in women, with varying prevalence among different ethnicities.

A woman's excessive hair growth and high testosterone were caused by a rare ovarian tumor, which was successfully treated with surgery.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.

Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.

Looking at skin can help find and treat serious diseases early.

Estrogens are key for bone growth spurts in both boys and girls and affect growth into adulthood.

Chrousos Syndrome is caused by mutations that make the body less sensitive to glucocorticoids, leading to various symptoms and requiring high-dose treatment.

Gonadal dysgenesis, like Turner's and Klinefelter's syndromes, negatively affects bone health, but hormone treatments can help.

The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.

Mutations in the NR3C1 gene cause a rare condition that affects hormone signaling and can lead to various symptoms, with dexamethasone as a treatment option.

Potassium channel openers show promise for treating heart disease and other conditions, but more research is needed to fully understand their effects and safety.

Sex hormone treatments can increase muscle mass in older adults but have inconsistent effects on muscle function and may carry cardiovascular risks.

New acne treatments include combination creams, advanced retinoids, and light therapies, focusing on safety and patient adherence.

The document lists various dermatology topics, treatments, and diagnostic methods.

Short telomeres contribute to aging and cancer, and while telomerase can delay aging, it may also promote cancer.

The document explains the genetic causes and characteristics of inherited hair disorders.

Diagnosing sex development disorders requires combining medical history, physical exams, imaging, lab tests, and genetic data.

The ketogenic diet might improve certain skin conditions, but more research is needed to confirm its effectiveness.