42 citations,
January 2021 in “Journal of Clinical Medicine” Microneedle arrays with nanotechnology show promise for painless drug delivery through the skin but need more research on safety and effectiveness.
2 citations,
February 2020 in “Rivista Urologia” Both terazosin and baclofen effectively reduce pain in young men with chronic testicular pain, with no difference in their effectiveness.
November 2024 in “Journal of Clinical Medicine” The treatment improved hair thickness, shine, and reduced hair loss effectively.
September 2019 in “Asian Journal of Pharmaceutical and Clinical Research” Teak seed extract is safe and reduces pain in mice.
May 2016 in “Mayo Clinic proceedings” A gluten-free diet fixed a man's severe stomach pain and bowel issue related to celiac disease, but not much his hair loss.
10 citations,
October 2014 in “Plastic & Reconstructive Surgery Global Open” Botulinum toxin type A injections improved hair growth and scalp health in a woman with radiation-induced hair loss.
February 2024 in “Curēus” Regional nerve blocks are better than ring blocks for pain relief during PRP hair treatment.
July 2023 in “Skin health and disease” Most UK survey participants had negative side effects from botulinum toxin injections, with many not fully recovering physically, emotionally, or financially.
144 citations,
September 2006 in “Clinics in Dermatology” Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.
8 citations,
May 2018 in “Primary Care: Clinics in Office Practice” Doctors should use a detailed patient history and physical exam to diagnose joint pain, and consult a rheumatologist early for suspected autoimmune diseases.
January 2019 in “Headache” Peripheral nerve blocks are a safe and effective way to treat various headaches and provide lasting pain relief.
April 2020 in “Journal of The American Academy of Dermatology” Microneedling with platelet-rich plasma can cause temporary, painful lymph node swelling in some patients.
140 citations,
December 2017 in “Journal of Controlled Release” Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.
27 citations,
January 2018 in “Curēus” Subcutaneous contraceptives can cause side effects like menstrual changes, headaches, weight gain, and pain at the implant site.
13 citations,
August 2012 in “Journal of the American Academy of Dermatology” A rare scalp condition causing hair loss and cysts in young men can be treated effectively with a specific steroid injection.
April 2019 in “Journal of Investigative Dermatology” Combining platelet-rich plasma injections and gel may effectively treat morphea, improving skin elasticity and reducing pain.
June 2020 in “Journal of Evolution of medical and Dental Sciences” Platelet Rich Plasma (PRP) treatment effectively reduces hair fall and increases hair growth in patients with Androgenetic Alopecia (AGA), but it may cause pain.
165 citations,
September 2003 in “Toxicology and applied pharmacology” Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.
114 citations,
March 2002 in “Current opinion in oncology/Current opinion in oncology, with cancerlit” Cancer therapy can cause various skin problems, including hair loss, skin darkening, painful hand-foot syndrome, and severe skin damage.
21 citations,
June 2019 in “Dermatologic Surgery” Platelet-rich plasma (PRP) treatment has been found effective in promoting hair growth for alopecia patients, with minimal side effects like temporary pain and redness.
1 citations,
May 2021 in “International Journal of Dermatology” Long hair follicular unit excision is effective for hair transplants, providing quick, natural-looking results with less pain but needs more time, staff, and skill.
March 2021 in “PARIPEX INDIAN JOURNAL OF RESEARCH” Microneedling combined with platelet-rich plasma therapy is more effective for hair regrowth in androgenic alopecia than microneedling alone, but it's more painful.
2 citations,
January 2022 in “Journal of the American Academy of Dermatology” Virtual reality can reduce pain during scalp injections.
87 citations,
September 2016 in “Journal of the American Academy of Dermatology” Intralesional triamcinolone effectively reduces pain and inflammation in hidradenitis suppurativa flares.
1 citations,
December 2023 in “Vestnik stomatologii i čelustno-licevoj hirurgii” Using hyaluronic acid fillers for a lateral temporal lift can cause serious blood vessel issues.
126 citations,
April 2015 in “Clinical, cosmetic and investigational dermatology” Choosing the right patients, using proper techniques, and having thorough knowledge are key to preventing and managing dermal filler complications.
105 citations,
September 1995 in “Journal of The American Academy of Dermatology” Recombinant cytokine therapy can cause skin reactions ranging from mild to severe.
24 citations,
October 2012 in “Journal of Ginseng Research” Korean Red Ginseng may help improve hair regrowth when used with corticosteroid injections for Alopecia Areata.
15 citations,
March 1981 in “Journal of The American Academy of Dermatology” Fiber implantation for pattern baldness was largely unsuccessful with many complications and is not recommended.
13 citations,
November 2018 in “Annals of Plastic Surgery” Nonshaven follicular unit extraction is a good hair transplant option that doesn't require shaving and can transplant up to 3000 grafts daily.