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In this case study, an 8-year-old boy with alopecia totalis experienced significant hair regrowth after baricitinib treatment, suggesting KRT74 variants may influence immune dysregulation in this condition.

The document concludes that permanent hair loss conditions are complex, require early specific treatments, and "secondary permanent alopecias" might be a more accurate term than "secondary cicatricial alopecia."

T cells and bacteria in the gut and skin help maintain health and protect against disease.

Some African American women experience central scalp hair loss, often linked to a history of fungal scalp infection.

This case report presents an instance of tufted hair folliculitis in a woman treated with trastuzumab, highlighting a previously unreported skin side effect of this selective HER2 inhibitor.

This study found that carbonic anhydrase II was significantly upregulated in human keratinocytes when treated with toll-like receptor 3 agonist and Th2 cytokines, suggesting its potential role in inflammatory skin conditions.

This case report describes a 25-year-old woman with alopecia areata and nail spooning, which regressed almost completely after treatment with oral corticosteroids.

This case report describes a 20-year-old female with favus caused by T. schöenleinii, which initially improved with antifungal treatment but recurred due to poor adherence, underscoring favus as an ongoing health issue in Turkey.

This article reviews the epidemiology, clinical evaluation, and pathogenesis of alopecia areata and highlights recent advancements, but it does not report new clinical findings.

This entry contains no research abstract, so no scientific findings or conclusions are reported.

This review summarizes the effects and complications of bariatric surgery on skin, noting it can alter existing skin conditions like psoriasis and trigger new dermatoses, but provides no new clinical results.

This review highlights the need for optimizing mesenchymal stromal/stem cell therapy through tailored in vitro strategies to unlock their full potential for treating specific diseases.

This study found that the spermidine analog N1-methylspermidine prolonged hair follicle growth and decreased inflammation and oxidative stress in cultured hair follicles, suggesting potential relevance for treating inflammatory scalp diseases.

This review explores the potential diagnostic and therapeutic applications of extracellular vesicles in treating various skin conditions but reports no new clinical study results.

This study found that deleting ceramide synthase 4 in skin epidermis stem cells disrupts hair follicle and skin barrier function, leading to immune responses similar to atopic dermatitis, due to imbalances in lipid composition affecting differentiation.

This review discusses the complex role of immune disturbances and the JAK-STAT pathway in alopecia areata, noting the success of JAK inhibitors in treatment, while highlighting ongoing debates and challenges in targeting other pathways like IL-17 and TNF-α.

This study found that children and adolescents with dermatological disorders had significantly higher rates of psychiatric comorbidity, including mood and anxiety disorders, compared to healthy controls.

This review outlines the existing understanding of alopecia areata, detailing its autoimmune nature, clinical presentation, histology, and management strategies, with corticosteroids highlighted as the most popular treatment option.

Early diagnosis and tailored treatment are crucial to prevent permanent hair loss and support self-esteem in children with scarring alopecia.

The document lists dermatology topics across life stages and notes hair loss can affect self-esteem and early skin cancer treatment is crucial.

This review explores the role of fatty acids and bioactive lipid mediators in skin health and suggests targeting this metabolic network to control inflammation and improve skin conditions, but it reports no new findings.

This abstract reviews the symptom of trichodynia, a painful scalp sensation linked to hair loss, and highlights its potential connection to inflammation but reports no new research findings.

This article reviews the causes, classification, and new treatments for pseudofolliculitis barbae but provides no new research findings.

This study found that alopecia areata is linked to genetic factors, specifically HLA haplotypes on chromosome 6, and involves immune privilege collapse at hair follicles which is mediated by the JAK-STAT pathway and pro-inflammatory cytokines like IFN-γ.

This study suggests that erosive pustular dermatosis of the scalp may be part of the spectrum of autoinflammatory dermatoses, rather than a unique skin disorder.

This review reports that various bioactive compounds in Aloe vera demonstrate significant anti-inflammatory, antioxidant, antibacterial, and immunomodulatory effects, supporting its validated use in treating metabolic disorders, gastrointestinal recovery, dermatological conditions, and wound healing due to its nutritional and therapeutic properties.

In this case report, researchers observed that a 47-year-old woman developed pityriasis amiantacea after using topical minoxidil, suggesting a potential new etiology for this scalp condition.

In this case report, a 65-year-old woman with lichen planopilaris achieved stabilization of her condition through early recognition and systemic corticosteroid therapy, emphasizing the critical role of coordinated management between primary care and dermatology.

This case study highlights the importance of a multidisciplinary approach in diagnosing and managing Vogt-Koyanagi-Harada syndrome, particularly emphasizing the role dermatologists can play in identifying early signs such as hair loss.

In this case report, the authors identified that sebaceous gland atrophy, traditionally associated with psoriatic or drug-induced alopecia, can also appear in seborrheic dermatitis, complicating the histopathological evaluation of alopecia biopsies and emphasizing the need to consider seborrheic dermatitis in differential diagnoses.