Manifestation of Pityriasis Amiantacea Following Initiation of Minoxidil

    April 2022 in “ JAAD case reports
    Albert G. Wu, Steven Barilla, Raman Madan
    TLDR A woman developed a rare scalp condition after starting minoxidil, which was resolved with specific shampoo and solution.
    The document presents a unique case of a 47-year-old woman who developed Pityriasis Amiantacea (PA), an uncommon inflammatory scalp condition, after initiating treatment with topical minoxidil 5% foam. PA is characterized by thick, adherent scales that bind to hair follicles, leading to hair matting and alopecia. The patient's symptoms persisted despite stopping the minoxidil and did not respond to topical treatments for scalp infection. She was diagnosed with PA based on clinical examination and history, and was prescribed ketoconazole 2% shampoo and clobetasol solution, which led to complete resolution of her symptoms within a month. This case emphasizes the multifactorial pathogenesis of PA and its potential to appear as a sequela of various conditions, treatments, and environmental factors. Early recognition and treatment of PA can prevent serious alopecic complications.
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