December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” In this preprint, an integrative regenerative protocol involving microneedling, plant-derived exosomes, and other therapies was used to treat androgenetic alopecia in an elderly woman, resulting in improved hair density and scalp coverage.
In this case-control study, researchers found that serum apelin-12 levels were significantly higher in acne patients and correlated with acne severity, BMI, insulin resistance, and inflammation, suggesting that managing insulin resistance could be important for acne treatment.
March 2025 in “Journal of Controlled Release” This study found that a biocomposite microneedle system, which includes selenium nanozyme and hypoxic extracellular vesicles, enhanced hair density and follicle diameter in androgenetic alopecia mice by fighting inflammation, promoting blood vessel growth, reducing reactive oxygen species, and counteracting androgen effects.
February 2024 in “ACS Omega” This study found that the topical Shen Bai hair growing decoction may improve androgenetic alopecia in mice by suppressing TNF-α and IL-6 levels, enhancing follicle density, and reducing apoptosis.
November 2023 in “International Journal of Pharmaceutics” This study found that a new transdermal drug delivery system using globefish skin collagen peptides and dissolving microneedles effectively promoted hair regrowth in mice with androgenetic alopecia by reducing inflammation and enhancing vascularization.
May 2015 in “Journal of The American Academy of Dermatology” The treatments for fungal nail infection, hair loss in men, benign nail tumor, and chemotherapy-associated nail bed inflammation are effective and safe.
September 2024 in “Ahmar Metastasis Health Journal” In this study on Wistar rats, ginger and celery extracts at the tested dosage did not significantly affect hair growth onset, duration, or regrowth, nor did they cause significant inflammation, despite the presence of bioactive phytochemicals in the extracts.
2 citations
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August 2023 in “Marine drugs” In this study, fish-derived collagen hydrolysate from tilapia scales improved hair growth and skin health in both cellular and mouse models, reducing oxidative stress and inflammation while enhancing hair quality and promoting beneficial gene expression.
March 2025 in “International Journal of Trichology” This study found that, in female patients with pattern hair loss, injections of adipose-derived stem cells increased hair density and thickness, reduced perifollicular inflammation, and enhanced markers associated with hair cycle regeneration.
February 2026 in “Medicina” This study found that intradermal injections of Profhilo® significantly reduced skin inflammation and pain, while altering spinal cord markers in mice with ovalbumin-induced atopic dermatitis, suggesting potential therapeutic benefits for inflammatory skin conditions involving both peripheral and central processes.
August 2024 in “Nature Communications” This study found that in female mice, softer, lightly crosslinked gelatin-based hydrogels promoted better wound healing with less scarring and inflammation compared to stiffer, heavily crosslinked hydrogels, affecting immune and stromal cell behavior.
56 citations
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November 2022 in “Biomolecules” This review explores the role of macrophage subsets in adult cutaneous wound healing and emphasizes their potential for therapeutic targeting, but reports no new experimental results.
2 citations
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February 2021 in “Developmental Cell” This study reports that aging in human skin involves early photo- and inflammation-related cellular changes, and suggests restoring KLF6 and HES1 expression might reverse some of these age-associated changes.
June 2026 in “Journal of Cosmetic Dermatology” PDRN may help with female hair loss, but more research is needed.
July 2024 in “Journal of Cosmetic Dermatology” This case study suggests that rose stem cell-derived exosomes, administered via noninvasive electroporation, may promote hair regeneration in androgenetic alopecia; larger studies are needed to confirm these findings.
290 citations
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December 2017 in “Journal of The American Academy of Dermatology” This article reviews the epidemiology, clinical evaluation, and pathogenesis of alopecia areata and highlights recent advancements, but it does not report new clinical findings.
108 citations
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December 2003 in “Lasers in surgery and medicine” This study found that combining near-infrared laser phototherapy with indocyanine green application may improve acne vulgaris by reducing active lesions and inflammation without side effects.
58 citations
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January 2015 in “International Journal of Trichology” This review evaluates the therapeutic potential of platelet-rich plasma for treating non-cicatricial alopecias and suggests it may be effective, though further research is needed to confirm its efficacy.
34 citations
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September 2019 in “Clinical, Cosmetic and Investigational Dermatology” This review covers the use of photobiomodulation devices for hair regrowth in various types of alopecia and reports no new clinical results.
16 citations
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February 1999 in “American Journal of Dermatopathology” This article describes a woman's case of slowly progressive nonscarring alopecia with unique biopsy findings, suggesting the need to reexamine similar cases currently classified as chronic diffuse alopecia areata.
14 citations
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January 2013 in “Journal of Cutaneous Medicine and Surgery” This study describes permanent scalp alopecia in patients receiving chemotherapy, radiation, or both, and highlights the need for further research to identify causative factors and mitigation strategies.
9 citations
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April 2005 in “PubMed” This study found that diffuse alopecia in female squirrel monkeys is associated with chronic telogen effluvium and appears to be predominantly age-related, potentially serving as an animal model for human diffuse alopecia.
7 citations
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May 2013 in “PubMed” In this randomized, placebo-controlled study, the tested cosmetic ingredient containing Trifolium pratense flower extract and a biomimetic peptide increased anagen hair and improved the anagen/telogen ratio over four months in individuals with recessing hair.
3 citations
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May 2018 in “Journal of nutritional health & food science” This review discusses the potential of a low-dose comprehensive cyclical nutrient therapy for enhancing hair growth and strengthening hair roots, but reports no new experimental results.
2 citations
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March 2022 in “Journal of Personalized Medicine” Personalized medicine is important for treating skin disorders, with new treatments and connections to hormones and genetics being explored.
2 citations
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July 2004 in “Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE” This study found that multiple treatments combining NIR laser phototherapy with ICG significantly reduced inflammation and improved skin condition in acne without side effects.
May 2026 in “Medical and Veterinary Entomology” This study found that the combination of L. sericata secretions and A. sintenisii extract significantly enhanced wound healing compared to each agent alone or Furacin®, suggesting a synergistic effect.
April 2026 in “Academia Polonica.” In this study, researchers explored the hormonal and biochemical factors linked to alopecia in women, highlighting how various factors such as nutrient deficiencies, hormonal imbalances, and stress may influence hair loss patterns, necessitating a comprehensive diagnostic and treatment approach in trichological practice.
January 2026 in “Archives of Internal Medicine Research” This review examines how regenerative therapies targeting shared biological pathways can promote healing in musculoskeletal disorders and hair follicle dysfunction, highlighting modalities like platelet-rich plasma and laser therapy while addressing challenges in standardization and measurement.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This study offers a new perspective on androgenetic alopecia, suggesting that hair loss at the vertex and frontal scalp results from mechanical and thermodynamic stress, alongside androgen activity, and proposes that reducing mechanical tension and improving local microcirculation could complement traditional treatments.