Successful Treatment of Female Pattern Hair Loss with Injection of Autologous Adipose-Derived Adult Stem Cells: A Controlled Clinical, Trichoscopic, and Immunohistochemical Trial

This study on 33 patients with female pattern hair loss (FPHL) found that intradermal injections of autologous adipose-derived adult stem cells (ADSCs) led to clinical improvement in hair volume for 75.75% of patients at 12 weeks, with 56% maintaining improvement at 24 weeks. Trichoscopic evaluations showed significant increases in terminal hair thickness and counts, and histopathological assessments indicated a reversal of hair follicle miniaturization in 93.9% of patients. Although improvements in perifollicular inflammation and fibrosis were observed, they were not statistically significant. The study suggests ADSC injections as a promising treatment for FPHL, with minimal side effects, and recommends further research with larger sample sizes.