Serum Level of Apelin-12 in Acne Patients: Is It a Marker of Disease Severity?

    April 2025
    Eman Youssef, Marwa Gaber, Amira Mohammed, Doaa About-Taleb
    Studysummary In this case-control study, researchers found that serum apelin-12 levels were significantly higher in acne patients and correlated with acne severity, BMI, insulin resistance, and inflammation, suggesting that managing insulin resistance could be important for acne treatment.
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    Research cited in this study 3

    1. Relation Between Acne Vulgaris and Metabolic Syndrome in Males The Medical Journal of Cairo University/˜The œMedical Journal of Cairo University · 2021
    2. Insulin Resistance in Androgenetic Alopecia and Acne Vulgaris Egyptian Journal of Dermatology and Venereology · 2019
    3. Role of Insulin, Insulin-Like Growth Factor-1, Hyperglycemic Food, and Milk Consumption in the Pathogenesis of Acne Vulgaris Experimental dermatology · 2009