research Testosterone Up-Regulates Vacuolar ATPase Expression and Functional Activities in Vas Deferens of Orchidectomized Rats
Testosterone increases acidification in the vas deferens by up-regulating V-ATPase.
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research Differential Activity of 2-Methylene-19-Nor Vitamin D Analogs on Growth Factor Gene Expression in Rhino Mouse Skin and Comparison to All-Trans Retinoic Acid
Some vitamin D analogs can thicken skin and reduce pore size like a common acne treatment, with one analog also affecting skin growth factors.
research New Populations with Increased Cardiovascular Risk: Cardiovascular Disease in Dermatological Conditions
Some skin conditions may increase the risk of heart disease, but are not yet included in cardiovascular prevention guidelines.
research Assessment of the Effect of Ficus Carica Leaf Extract on B16F10 Melanoma Cancer Cells: The Roles of p53, Caspase-3, and Caspase-9 in Inducing Intrinsic Apoptosis Cascade
Ficus carica leaf extract may help treat melanoma by promoting cancer cell death without harming normal cells.
research Analysis of Bimatoprost-Induced Changes on Rabbit Eyelash Follicle: Clinical and Electron Microscopic Study
Bimatoprost eye drops make rabbit eyelashes longer, thicker, and darker, and increase the number of lashes without causing inflammation.
research Hyperandrogenism and Cardiometabolic Risk in Pre- and Postmenopausal Women: What Is the Evidence?
Hyperandrogenism increases heart disease risk in premenopausal women, but this risk is linked to obesity in postmenopausal women.
research Deletion of Myelin Protein Zero-Like 3 Increases Sebaceous Gland Size and Sebocyte Proliferation but Reduces Skin Adipose Depots: Can MPZL3 Inhibition Promote Excessive Loss of Lipids via Sebum Hypersecretion?
Deleting MPZL3 increases skin oil production and reduces body fat.
research Effect of High Levels of Testosterone on Cardiovascular Risk in Polycystic Ovary Syndrome
High testosterone increases heart disease risk in women with PCOS.
research Loose Anagen Syndrome
Loose anagen syndrome causes easy hair shedding in children, often resolving on its own.
research Placebo Response in Alopecia Studies
Placebo effects in alopecia treatments are likely due to study design, not real improvement.
research Why Are Men With Premature Alopecia at Higher Risk of Benign Prostatic Hyperplasia? And What About Prostate Cancer?
Men with early hair loss may have a higher risk of enlarged prostate and possibly prostate cancer due to shared hormonal factors.
research A Study for Verification of Hair Growth Effect of Azelaic Acid and Vitamin B6
Azelaic acid and vitamin B6 together may improve hair growth.
research Gut Inflammation Induced by Finasteride Withdrawal: Therapeutic Effect of Allopregnanolone in Adult Male Rats
Allopregnanolone can reduce gut inflammation and normalize neurotransmitter levels after finasteride withdrawal.
research A Comprehensive Review on Metabolic Syndrome
Managing metabolic syndrome needs both lifestyle changes and medical treatments.
research Assessment of Cardiovascular Risk and Prevention of Cardiovascular Disease in Women with Polycystic Ovary Syndrome: A Consensus Statement by the Androgen Excess and Polycystic Ovary Syndrome Society
Women with PCOS should be screened for heart disease risk and manage their health to prevent it.
research Complications of Cushing's Syndrome: State of the Art
Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.
research Age-Associated Inflammation Inhibits Epidermal Stem Cell Function
Aging causes skin stem cells to work less effectively.
research A Polygenic Mouse Model of Psoriasiform Skin Disease in CD18-Deficient Mice
CD18-deficient mice developed psoriasis-like skin disease, useful for studying inflammatory skin disorders.
research Telogen Effluvium: New Concepts and Review
The document says there are five types of hair loss conditions and different causes, including drugs.
research Neuronal Plasticity of the Brain-Skin Connection: Stress-Triggered Up-Regulation of Neuropeptides in Dorsal Root Ganglia and Skin via Nerve Growth Factor-Dependent Pathways
Stress increases certain chemicals in the skin and nerves, which might worsen skin conditions.
research Relation of Skin Polyamines to the Hairless Phenotype in Transgenic Mice Overexpressing Spermidine/Spermine N1-Acetyltransferase
Excessive putrescine causes hair loss in transgenic mice by disrupting hair follicle development.
research CRISPR/Cas9-Mediated Loss of FGF5 Function Increases Wool Staple Length in Sheep
Disabling the FGF5 gene in sheep leads to longer wool.
research Promotive Effect of Minoxidil Combined with All-Trans Retinoic Acid (Tretinoin) on Human Hair Growth In Vitro
Minoxidil and ATRA together boost hair growth more effectively than minoxidil alone.
research Disturbed Keratinocyte Differentiation in Transgenic Mice and Organotypic Keratinocyte Cultures Due to Spermidine/Spermine N1-Acetyltransferase Overexpression
Overexpression of SSAT causes hair loss and skin issues, but reducing putrescine can help.
research Androgenetic Alopecia and Risk of Prostate Cancer: A Systematic Review and Meta-Analysis
Vertex pattern hair loss linked to higher prostate cancer risk.
research Premature Adrenarche: Early Maturation of Adrenal Glands in Children
Early adrenal gland maturation in young children can be normal, but other serious conditions should be ruled out first.
research Dietary Isoflavone Increases Insulin-Like Growth Factor-I Production, Thereby Promoting Hair Growth in Mice
Eating isoflavone can help mice grow hair by increasing a growth factor.
research Relationship Between Serum Concentrations, Hemodynamic Effects, and Cardiovascular Lesions in Dogs Treated with Minoxidil
Higher minoxidil doses in dogs cause faster heart rate, lower blood pressure, and heart issues.
research Polycystic Ovary Syndrome in Adolescence and Type 2 Diabetes
Girls with PCOS during adolescence have a higher risk of developing type 2 diabetes, and early treatment can help manage this risk.
research Skin Climacteric Aging and Hormone Replacement Therapy
HRT helps improve skin issues caused by menopause.