December 2023 in “International journal of research in dermatology” This study found that using 'moha: 5-in-1' hair oil for 8 weeks significantly reduced hair fall, increased hair growth rate and thickness, and decreased scalp dandruff among healthy adults with alopecia, with no adverse effects reported.
129 citations
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October 2000 in “British Journal of Dermatology” This study found that finasteride increases anagen hair growth in men with androgenetic alopecia.
32 citations
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May 2017 in “Lasers in medical science” This study found that radiofrequency treatment, with or without hydrolyzed collagen, increased dermis thickness, neocollagenesis, and FGF2 overexpression in rat skin tissue.
25 citations
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May 2020 in “Stem Cells Translational Medicine” In this randomized clinical trial, the authors reported that adipose-derived stem cell constituent extract topical solution increased hair density and thickness in patients with androgenetic alopecia over 16 weeks compared to placebo.
22 citations
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August 2019 in “Environmental research” This study found that the Pseudomonas sp. T5-6-I strain significantly increased selenium accumulation and root hair density in Brassica oleracea, highlighting its potential for phytoremediation and biofortification.
20 citations
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July 2020 in “Expert Opinion on Biological Therapy” This study found that combining micro-needling, low-level laser therapy, and autologous non-activated platelet-rich plasma increased hair density in patients with androgenic alopecia over the treatment period.
14 citations
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July 2019 in “Experimental and Molecular Medicine” This study suggests that the secretome from amniotic fluid-derived mesenchymal stem cells overexpressing Nanog could stimulate hair growth and increase follicle density, potentially aiding in alopecia treatment.
9 citations
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January 2018 in “Dermatologic Therapy” In this study, the HairLux fractional radiofrequency device was found to be effective and safe for stimulating hair growth in androgenetic alopecia, with patients experiencing increased hair density and thickness after ten treatments.
2 citations
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January 2022 in “Lasers in Medical Science” This pilot study reported significant improvement in hair restoration and patient satisfaction with the use of fractional carbon dioxide laser followed by platelet-rich plasma, showing greater hair density increases using higher laser pulse energy settings in individuals with androgenetic alopecia.
2 citations
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January 2011 in “The Korea Journal of Herbology” In this study, the herbal hair tonic and natural food treatment in C57BL/6 mice were associated with increased hair density and thickness compared to controls, suggesting potential hair growth benefits.
1 citations
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July 2024 in “Syntax Literate Jurnal Ilmiah Indonesia” In this study, topical application of 5% minoxidil significantly increased hair follicle density in a mouse model of androgenetic alopecia, as evidenced by a rise in density from 24.00 in the control group to 40.14 in the treatment group.
1 citations
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April 2023 in “Biomolecules” This study found that hair care products containing fermented papaya, fermented mangosteen, and caffeine significantly inhibited hair loss, increased hair density and thickness, and improved hair follicle structure in individuals with androgenic or diffuse alopecia over three months compared to placebo and caffeine controls.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study evaluated an Ayurvedic treatment protocol for Indralupta (similar to alopecia areata), finding significant clinical improvement with increased hair density and no adverse effects, suggesting it may be a safe, holistic alternative for managing alopecia areata.
May 2026 in “International Journal of Homoeopathic Sciences” In this case report, long-term classical homeopathic management of a woman with advanced female pattern baldness led to significant hair stabilization, improved scalp health, increased hair density, and notable psychosocial benefits, despite previous treatment failures.
February 2026 in “International Journal of Cosmetic Science” This study found that a novel Mito-Activator Complex, containing nicotinamide and epigallocatechin gallate, significantly increased hair density and growth in a 6-month human trial, with no adverse effects reported, potentially offering a new approach to hair loss treatment through mitochondrial activation.
January 2026 in “Materialia” In this study, porcine collagen acellular dermal matrix scaffolds combined with mice platelet-rich plasma were associated with increased hair density and follicle regeneration in mice with alopecia, suggesting a potential therapeutic approach.
January 2026 in “Dermatologic Therapy” In this prospective study, individuals with androgenetic alopecia using a home-use low-level laser therapy helmet for 48 weeks experienced significant increases in hair density and thickness, with reported improvements consistent across sexes and no device-related adverse events.
September 2025 in “Frontiers in Medicine” This study assessed the effectiveness of various combinations of minoxidil with other agents for androgenetic alopecia, finding that platelet-rich plasma and basic fibroblast growth factor combined with minoxidil significantly increased hair density, while different combinations were optimal depending on gender.
May 2025 in “International Ayurvedic Medical Journal” In this case report, a 19-year-old male with alopecia areata showed complete relief from symptoms and increased hair density after 90 days of Shamana therapy, suggesting its potential effectiveness in treating this condition with minimal side effects.
April 2025 in “Journal of Cosmetic Dermatology” In this pilot study, the niostem device, a wearable device delivering low-level electrical stimulation, significantly increased hair density by 19.3% and thickness by 8.8% in male androgenetic alopecia patients over six months without reported adverse events.
August 2024 in “Skin Research and Technology” This case study involving a 63-year-old woman with female pattern hair loss found that a 3-month regimen of low-dose oral minoxidil increased hair density from 98 to 140 hairs per square centimeter, but caution was advised regarding its safety and efficacy without larger trials.
July 2024 in “Skin Appendage Disorders” This study found that after 6 months of taking an oral supplement, patients with chronic telogen effluvium or androgenetic alopecia experienced a statistically significant increase in hair density and overall improved hair appearance compared to those taking a placebo, with the supplement being well tolerated.
May 2024 in “Dermatologic surgery” In this study involving 15 women with alopecia, subcutaneous scalp injections of platelet-rich plasma every four weeks for three sessions led to increased hair and hair follicle density at 24 weeks, with common side effects being local swelling and pain.
April 2024 in “International journal of clinical trials” In this study, researchers found that a standardized extract of Sesbania grandiflora (SesZen-Bio™) improved hair density and thickness, as well as increased serum ferritin levels, over an 8-week period among participants, suggesting enhanced keratin production and follicle growth.
January 2024 in “Journal of Natural Remedies” This study found that the petroleum ether extract of Solanum nigrum may promote hair regrowth in testosterone-induced hair loss in rats, as indicated by increased follicle density and anagen/telogen ratio.
November 2023 in “Clinical, Cosmetic and Investigational Dermatology” This study found that both oral and topical formulations of VISPOTM, a saw palmetto oil, significantly reduced hair fall and increased hair density in subjects with androgenetic alopecia, with no serious adverse effects observed.
June 2023 in “Trichology and cosmetology:” This study found that 12-week oral supplementation of Ageratum conyzoides extract significantly reduced hairline recession and affected prostaglandin levels in adults with hair loss, though hair density increases were not statistically significant, and no improvements were found in other hair loss measures compared to placebo.
November 2022 in “Nihon Nyuusankin Gakkaishi/Nihon Nyūsankin Gakkaishi” In a non-blinded study with 12 Japanese participants, applying a lotion containing Lactiplantibacillus plantarum N793 to the scalp for 24 weeks significantly increased hair density and reduced hair loss, with participants reporting improvements in hair thickness and volume, and the treatment deemed safe.
September 2011 in “대한미용학회지” In this study, topical application of 5% bear oil on C57BL/6 mice accelerated hair regrowth and increased hair follicle depth and size more than 2% bear oil, minoxidil, or ethanol.
September 2022 in “International Journal of Trichology” This study found that trichoscopic measurements of hair density and diameter are useful for assessing the severity of female pattern hair loss and its progression.