297 citations,
December 2005 in “Journal of controlled release” P-SLN nanoparticles effectively deliver podophyllotoxin to the skin.
19 citations,
August 2012 in “Cell death and differentiation” Intu gene is crucial for hair follicle formation by helping keratinocytes differentiate through primary cilia.
1 citations,
April 2022 in “Applied sciences” Bitter melon extract may help prevent hair loss and can be used in cosmetic products.
88 citations,
August 2014 in “PLOS genetics” Syndecan-1 is essential for maintaining skin fat and preventing cold stress.
1 citations,
May 2001 in “Pharmacology & Toxicology” Cyproterone acetate may cause liver cancer at high doses, but is considered safe at recommended doses for approved uses.
99 citations,
April 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair follicles help skin immune recovery after UVB exposure.
18 citations,
January 2020 in “Indian Dermatology Online Journal” Platelet-rich plasma shows potential for hair loss and skin rejuvenation but needs more research for widespread use.
13 citations,
May 2021 in “FASEB bioAdvances” Plant-based products can improve hair and skin health without harmful side effects.
14 citations,
November 2018 in “Journal of drug delivery and therapeutics” Ethosomes are effective, safe carriers for delivering drugs through the skin.
5 citations,
August 2022 in “Mediators of Inflammation” The study assessed the efficacy and safety of combining Pulsed Dye Laser (PDL) with Pingyangmycin (PI) for treating hyperplastic scars after acne in 109 patients. The research group (n=52) receiving both PDL and PI showed significantly better scar repair, skin texture, and patient comfort compared to the control group (n=57) receiving only erbium fractional laser treatment. The combination therapy resulted in higher total effective rates (90.38% vs. 75.44%), better psychological outcomes, and higher treatment satisfaction, with no significant difference in adverse reactions between the groups. The study concluded that PDL combined with PI is a promising and safe option for managing hyperplastic scars.
July 2024 in “Journal of Controlled Release” The study developed tofacitinib-loaded cationic lipid nanoparticles (TFB-cNLCs) to enhance percutaneous absorption and hair follicle targeting for treating alopecia areata. Using ex vivo pig ear and in vitro follicle models, TFB-cNLCs demonstrated improved drug delivery to hair follicles, reduced IFN-γ-induced symptoms, and decreased CD8+NKG2D+T cells in a C3H mouse model, effectively reversing hair loss. This formulation offers a promising topical treatment, minimizing systemic side effects while maintaining efficacy.
November 2015 in “Pharmacy & pharmacology international journal” Jamun fruit pulp extract is better at promoting hair growth than seed extract.
18 citations,
June 2019 in “Clinical research in dermatology” Acne can't be cured but can be managed with treatments like benzoyl peroxide and diet changes; it's costly and can lead to scarring and mental health issues.
March 2023 in “Journal of clinical pharmacy and therapeutics” Isoliensinine, a natural compound, prevents stress-related hair greying by blocking a specific receptor on hair cells.
1 citations,
April 2023 in “Scientific Reports” Self-assembling RADA16-I hydrogels with bioactive peptides significantly improve wound healing.
99 citations,
September 2007 in “The American journal of pathology” Chemotherapy damages hair follicles, causing hair loss and other cellular changes.
2 citations,
January 2016 in “Advanced biomedical research” The hair wax with propolis and Eruca sativa seed oil promotes hair growth effectively.
179 citations,
June 2000 in “The American journal of pathology” The absence of functional sebaceous glands causes hair follicle destruction and scarring alopecia.
12 citations,
August 2022 in “Journal of Controlled Release” A new microneedle patch effectively promotes hair growth by increasing blood vessel formation around hair follicles.
4 citations,
November 2021 in “Pharmaceuticals” Paeonia lactiflora and Poria cocos extracts can potentially increase hair growth and reduce hair loss symptoms by lowering testosterone and inflammation levels.
1 citations,
October 2018 in “InTech eBooks” Ethosomes are a promising method for treating hair loss by delivering drugs directly to the scalp.
30 citations,
June 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Plet-1 protein helps hair follicle cells move and stick to tissues.
July 2024 in “International Journal of Molecular Sciences” RF-based therapies might help treat hair loss.
6 citations,
January 2020 in “Skin Pharmacology and Physiology” HIF-1α stimulators, like deferiprone, work as well as popular hair loss treatments, minoxidil and caffeine, in promoting hair growth.
5 citations,
January 2018 in “Skin appendage disorders” Minoxidil base is preferred for hair loss treatment, but minoxidil sulfate may be an alternative for unresponsive patients.
1 citations,
January 2023 in “Skin appendage disorders” Hair oils can worsen seborrheic dermatitis in black patients.
2 citations,
January 2022 in “Skin appendage disorders” A combination of methotrexate injections and CO2 laser treatment led to complete hair regrowth in two patients with hard-to-treat alopecia.
May 2023 in “Skin research and technology” A DNA aptamer helps promote hair growth by enhancing a key cell growth signal in hair follicle cells.
15 citations,
September 2008 in “Archives of Dermatological Research” Roxithromycin, an antibiotic, can increase hair growth and might be used as a treatment for hair loss.
Silk sericin dressing with collagen heals wounds faster and improves scar quality better than Bactigras.