March 2018 in “Suez Canal University Medical Journal” This review examines targeting the JAK-STAT pathway in inflammatory skin diseases, highlighting existing JAK inhibitors and potential developments, but presents no new experimental or clinical results.
June 2026 in “Research Square” This report on a case of alopecia areata in a mother and daughter with a 16-year gap suggests genetic predisposition and environmental triggers rather than direct transmission.
September 2025 in “Dermatology and Therapy” This study reviewed the burden of alopecia areata in the UAE, noting limited regional data on patient demographics and treatments but highlighting the approval and promising results of the Janus kinase inhibitor baricitinib for managing this condition.
40 citations
,
March 2019 in “Nature Communications” This study found that deleting Stim1 and Stim2 in mature T regulatory cells disrupts Ca 2+ signaling, preventing their differentiation and leading to severe autoimmune disorders in mice.
36 citations
,
July 2020 in “Frontiers in Medicine” Spironolactone might help protect against severe lung problems in COVID-19 patients.
28 citations
,
March 2016 in “Toxicologic pathology” This review discusses the function and pathology of hair follicles and highlights the potential of using dogs as a model to study human hair and stem cell disorders, but presents no new experimental results.
4 citations
,
January 2020 in “Lasers in Surgery and Medicine” This study found that combining a 308-nm excimer lamp with minoxidil led to significant hair regrowth in alopecia areata patients, with side effects like hyperpigmentation being tolerable.
3 citations
,
September 2019 in “Journal of Orthodontics” In this study, a 13-year-old boy developed temporary pressure alopecia from wearing orthodontic headgear, which resolved after discontinuation, highlighting a rare side effect that can affect psychosocial wellbeing.
2 citations
,
July 2024 in “Cureus” This review discusses the potential benefits of using autologous endometrial cells and PRP via hysteroscopic injections to improve pregnancy outcomes in ART, particularly in individuals with refractory thin endometrium, but reports no new clinical results.
May 2025 in “Journal of Diverse Medical Research Medicosphere” This article reports a rare case of angioedema in a pregnant woman with systemic lupus erythematosus, highlighting a need for further research in this area.
January 2020 in “Journal of Entomology and Zoology Studies” This study found that canine hair follicle stem cells are located in the isthmus/bulge region of the hair follicle, surrounded by telocytes.
March 2015 in “Plastic and reconstructive surgery” This chapter reviews the skin's structure and its clinical relevance, highlighting connective tissue diseases and the potential for novel treatments like protein, cell, or stem cell transfer, but reports no new findings.
14 citations
,
July 2021 in “Reviews in endocrine and metabolic disorders” This study explores how SARS-CoV-2 interacts with endocrine organs and highlights specific endocrine molecules that help explain the progression and outcomes of COVID-19, especially in patients with certain metabolic conditions.
5 citations
,
March 2019 in “Scientific Reports” This study reports that the side population technique can isolate melanocyte stem cells from human hair follicles, potentially allowing them to be used for skin pigmentation repopulation.
70 citations
,
January 2014 in “International review of cell and molecular biology” This review discusses the role of keratins in maintaining epidermal structure and function and reports no new results; the authors emphasize the lack of rational therapies for skin disorders linked to keratin mutations.
63 citations
,
December 1988 in “International Journal of Dermatology” Vitiligo causes white skin patches and is linked to autoimmune issues.
8 citations
,
March 1979 in “International Journal of Dermatology” Dr. Vera H. Price's 1979 work emphasizes the importance of accurate diagnosis and personalized treatment for hair loss.
1 citations
,
January 2012 in “Elsevier eBooks” The document concludes that the skin is a complex organ providing protection, sensation, and healing, with challenges in treating conditions like itchiness.
July 2018 in “Elsevier eBooks” This review discusses the diagnosis of alopecia in psoriasis, highlighting different hair loss types and the need to distinguish it from similar conditions, but reports no new clinical results.
28 citations
,
March 2010 in “Histochemistry and Cell Biology” This study identified specific markers that can distinguish between stem cells in different regions of human scalp hair follicles, offering potential strategies for cell sorting and purification based on these markers.
18 citations
,
March 2006 in “Expert Review of Neurotherapeutics” This review outlines strategies for preventing, identifying, and managing complications related to current MS therapies and reports no new clinical results, emphasizing the growing complexity in MS treatment regimens.
1 citations
,
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that oral tofacitinib improved disease activity in patients with lichen planopilaris, suggesting it may be a promising treatment option for this condition.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” This phase 2a trial evaluated Samcyprone for common wart treatment and found that while a sensitization reaction is necessary for therapeutic response, its level does not predict wart clearance.
306 citations
,
April 2019 in “International Journal of Molecular Sciences” This review discusses the protective roles of skin-resident immune cells in maintaining tissue homeostasis and facilitating wound healing, but reports no new experimental findings.
75 citations
,
November 2016 in “Medicines” This review discusses the properties and therapeutic potentials of beta-sitosterol, highlighting a need for more detailed studies on its mechanisms and long-term effects in humans; it reports no new results.
70 citations
,
February 2015 in “Expert Opinion on Drug Discovery” This review discusses current knowledge on the biological mechanisms of different types of alopecia but reports no new clinical findings; the authors highlight future research directions, especially regarding epidermal stem cells and immune pathways.
47 citations
,
March 2016 in “Journal of dermatology” This review discusses various rare syndromes associated with ichthyosis and emphasizes the importance of understanding their molecular genetics and mechanisms for developing effective treatments and genetic counseling, but it reports no new clinical findings.
43 citations
,
March 2011 in “Journal of psychosomatic research” This study found that children with alopecia areata experienced more stressful life events and excreted higher levels of catecholamines compared to healthy siblings.
43 citations
,
February 2019 in “International immunology” This review examines the role of regulatory T cells in skin immune disorders, highlighting their unique functions in conditions like scleroderma, alopecia areata, and psoriasis, without reporting new clinical results.
39 citations
,
September 2017 in “The Open Rheumatology Journal” This review discusses the role of complement activation in SLE and suggests that while monitoring C3 and C4 remains important, increased levels of cell-bound complement activation products may better indicate disease activity.