Enhancing Endometrial Health in Assisted Reproductive Technology: Evaluating Autologous Endometrial Cells and Platelet-Rich Plasma via Hysteroscopic Injections

July 2024 in “ Cureus ”

Priti Karadbhajne, Akash More, Hellen Y Dzoagbe

Studysummary This review discusses the potential benefits of using autologous endometrial cells and PRP via hysteroscopic injections to improve pregnancy outcomes in ART, particularly in individuals with refractory thin endometrium, but reports no new clinical results. Our plain-language summary of this paper — not a Tressless recommendation.

This review article evaluates the use of autologous endometrial cells and platelet-rich plasma (PRP) via hysteroscopic injections in assisted reproductive technology (ART) to improve endometrial health. The analysis of several trials indicates that these injections can enhance endometrial thickness and receptivity, thereby increasing the likelihood of pregnancy and successful delivery, particularly in individuals with refractory thin endometrium. The findings suggest that autologous PRP and minimally altered endometrial cellular treatments hold promise for improving ART outcomes, especially for those experiencing implantation difficulties.

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