222 citations,
September 2016 in “JCI insight” Tofacitinib is safe and effective for severe alopecia areata, but hair loss may return 2 months after stopping treatment.
205 citations,
March 2012 in “Science Translational Medicine” PGD2 stops hair growth and is higher in bald men with AGA.
3 citations,
May 2022 in “Experimental Dermatology” Misbehaving hair follicle stem cells can cause hair loss and offer new treatment options.
1 citations,
May 2018 in “Journal of Investigative Dermatology” Fzd2 is important for skin and hair development through various signaling ways.
February 2024 in “International Journal of Molecular Sciences” Hair loss in Androgenetic Alopecia is caused by genetics, aging, and lifestyle, leading to hair follicle shrinkage and related health risks.
April 2018 in “Journal of Investigative Dermatology” Both Th1 and Th2 immune responses are increased in alopecia areata, with Th2 response more strongly linked to how severe the disease is.
11 citations,
October 2021 in “Frontiers in Cell and Developmental Biology” Non-coding RNAs are important for hair growth and could lead to new hair loss treatments, but more research is needed.
24 citations,
August 2017 in “Prostaglandins & Other Lipid Mediators” CRTH2 antagonists might be useful for treating many conditions because they play a role in immune and inflammation responses.
1 citations,
April 2020 in “Baylor University Medical Center Proceedings” Microneedling with triamcinolone helps hair regrowth in ophiasis alopecia areata.
7 citations,
January 2019 in “Pharmaceutical Biology” Eclipta prostrata helps hair growth and maintains the growth phase by affecting certain growth factors.
5 citations,
September 2021 in “Frontiers in Cell and Developmental Biology” Dihydrotestosterone treatment on 2D and 3D-cultured skin cells slows down hair growth by affecting certain genes and could be a potential target for hair loss treatment.
January 2015 in “Przegla̧d dermatologiczny” 308 nm excimer light therapy may help hair regrowth in alopecia areata with delayed results and no serious side effects.
November 2022 in “Skin health and disease” People with hair loss conditions often have more mental health issues like depression and anxiety compared to those without hair loss.
1 citations,
July 2023 in “Journal of Clinical Medicine” Different causes of beard hair loss have various treatments, including medications, lifestyle changes, and procedures to stimulate hair growth.
4 citations,
June 2021 in “Frontiers in Pharmacology” Bone marrow stem cells and their medium help hair regrowth.
July 2022 in “JEADV Clinical Practice” The document concludes that different types of permanent hair loss conditions are related and early treatment is key to preventing further damage.
December 2017 in “Elsevier eBooks” The vitamin D receptor helps maintain hair and bone health even without binding vitamin D.
45 citations,
August 2018 in “Stem Cells International” Stem cells, especially from fat tissue and Wharton's jelly, can potentially regenerate hair follicles and treat hair loss, but more research is needed to perfect the treatment.
14 citations,
July 2022 in “Nutrients” Vitamin A is important for healthy skin and hair, influencing hair growth and skin healing, but UV light reduces its levels.
March 2024 in “International Journal of Pharmaceutics” Ginsenoside Rg3 combined with minoxidil was more effective in treating hair loss in mice.
6 citations,
February 2021 in “Frontiers in Cell and Developmental Biology” Eating too much or too little vitamin A can cause hair loss.
November 2023 in “Cell Proliferation” A protein from fat-derived stem cells, DKK1, is linked to hair loss and blocking it may help treat alopecia areata.
July 2023 in “Biomolecules” The circadian clock plays a key role in hair growth and its disruption can affect hair regeneration.
161 citations,
October 2012 in “Seminars in cell & developmental biology” Hair growth and development are controlled by specific signaling pathways.
133 citations,
September 2013 in “Nature Reviews Molecular Cell Biology” Different types of stem cells and their environments are key to skin repair and maintenance.
2 citations,
January 2023 in “International Journal of Biological Sciences” A specific pathway involving AR, miR-221, and IGF-1 plays a key role in causing common hair loss.
March 2020 in “Clinical research in dermatology” Two unusual cases showed that Lichen Planopilaris can look like other skin conditions and need early treatment to protect hair.
1 citations,
June 2023 in “JAAD case reports” Nivolumab treatment led to hair regrowth in a man with metastatic melanoma and alopecia areata.
35 citations,
January 2006 in “Journal of Dermatological Treatment” Zinc can help with some skin problems, but its effectiveness varies depending on the condition.
11 citations,
August 2021 in “Aging” Collagen and TGF-β2 help maintain hair cell shape and youthfulness.