October 2025 in “Journal of Pharmacy And Bioallied Sciences” In this observational study conducted at a tertiary care center, researchers found that post-COVID patients most commonly experienced telogen effluvium and other dermatological issues like herpes infection and acne, with middle-aged and female patients being predominantly affected.
This review discusses various treatment options for alopecia areata, focusing on manipulating the immune response around hair follicles, but reports no new clinical results.
17 citations
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July 2019 in “Lupus Science & Medicine” In this study, gene expression analysis of plucked hair follicles from scalp lesions was sufficient to differentiate chronic discoid lupus erythematosus from psoriasis and healthy controls, suggesting a non-invasive diagnostic potential.
September 2025 in “International Journal of Molecular Sciences” This review reports on the potential for deucravacitinib, an oral TYK2 inhibitor approved for psoriasis, to treat various immune-mediated diseases, with emerging research suggesting possible uses in neurodegenerative diseases and certain cancers.
In this study, researchers found that alopecia areata is linked to immune cell activation against hair follicle autoantigens and is associated with heart changes and cardiac marker alterations in humans and mice.
August 2014 in “Warwick Research Archive Portal (University of Warwick)” This study found that obesity in women may impair endometrial stromal function and contribute to reproductive complications, possibly due to metabolic influences rather than immune cell differences.
This study found that acute stress can cause rapid hair loss by triggering necrosis in hair follicle cells and initiating autoimmunity, revealing a mechanism where stress-induced nerve activity leads to tissue damage and immune system activation.
6 citations
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November 2024 in “Frontiers in Immunology” This review examines the role of autophagy, specifically macrophage, chaperone-mediated, and microphagy, in the progression of six skin diseases, including psoriasis and systemic lupus erythematosus, illustrating its significance in cellular homeostasis.
August 2023 in “Physician's journal of medicine” This review provides a detailed overview of Hashimoto thyroiditis, discussing its epidemiology, risk factors, genetic and environmental contributors, clinical presentations, diagnostic methods, and treatment options, emphasizing the importance of personalized treatment plans due to varied causes and symptoms.
13 citations
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April 2022 in “Frontiers in oncology” This review discusses the early phases of melanomagenesis and the factors influencing melanoma cell variability and reports no new clinical results.
135 citations
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December 2015 in “Expert Opinion on Biological Therapy” This review synthesizes recent research on exosomes, highlighting their role as key modulators in regenerative outcomes and suggesting they may offer advantages over stem cell-based therapies in process and regulation.
10 citations
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December 2019 in “in Vivo” This study found that administering testosterone to ovariectomized female rats decreased endometrial tight junction complexity and expression of specific proteins, potentially affecting embryo implantation.
3 citations
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June 2006 in “Expert Review of Dermatology” This review discusses recent advances in hair follicle research, highlighting therapeutic and cosmetic applications, but reports no new study results.
This review highlights the increasing global incidence and broad socio-economic impact of celiac disease, emphasizing the need for improved recognition and management to address its multidimensional implications, including comorbidities and dietary challenges.
July 2025 in “Journal of Cosmetic Dermatology” In this study, authors present a case where a 26-year-old patient with alopecia areata experienced relapse after initially responding to Tofacitinib, mitigated by corticosteroids, highlighting challenges and potential insights into the treatment and pathogenesis of the condition.
24 citations
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July 2021 in “Pharmaceutics” This article reviews the JAK signaling pathway and the development of ruxolitinib cream as a targeted treatment for inflammatory skin diseases, reporting no new clinical results.
October 2025 in “International Journal of Dermatology” In this study, 49% of patients with alopecia areata achieved a significant response to baricitinib, with a lower baseline severity, shorter disease duration, and longer treatment duration identified as significant predictors of treatment success.
11 citations
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August 2021 in “Stem Cell Research & Therapy” This study found that coadministration of pimecrolimus may interfere with the therapeutic efficacy of mesenchymal stem cell therapy in atopic dermatitis.
March 2026 in “Virulence” This narrative review suggests that intermediate filaments like vimentin and keratin play a significant role in various stages of viral infection, presenting potential antiviral intervention targets.
3 citations
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July 2023 in “International journal of molecular sciences” This review discusses the association between emotional stress-related neuropeptides and the pathogenesis of alopecia areata, reporting no new experimental findings.
January 2020 in “Columbia Academic Commons (Columbia University)” This study utilized targeted genomic sequencing and whole exome sequencing to identify novel common and rare genetic variants in Alopecia Areata, revealing potential mechanisms contributing to disease susceptibility.
August 2026 in “Molecular Biomedicine” This review outlines the design and engineering of multifunctional hydrogels, emphasizing their evolving biomedical applications, notably in controlled drug delivery, tissue support, and disease management, and discusses their potential for clinical translation.
6 citations
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August 2025 in “Frontiers in Bioengineering and Biotechnology” This review discusses the evolution of platelet concentrates in regenerative medicine, highlighting a proposed function-driven classification that distinguishes three generations of PCs by biological activity rather than development order, with third-generation exosome-based therapies showing superior therapeutic efficacy over earlier formulations.
29 citations
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March 2001 in “Clinics in Dermatology” This article discusses various types of primary cicatricial alopecias and reports no new clinical results; it emphasizes the importance of accurate diagnosis for effective management.
March 2026 in “Clinical Cosmetic and Investigational Dermatology” In this case study, treatment with the selective JAK1 inhibitor upadacitinib significantly improved symptoms in a patient with refractory alopecia areata, vitiligo, ankylosing spondylitis, and allergic asthma-nasal syndrome, though a transient liver function abnormality was noted.
27 citations
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January 2020 in “Experimental Dermatology” This review discusses the role of immune cells in mammalian hair cycle control and highlights their potential relevance to human hair cycling disorders, reporting no new clinical findings.
February 2026 in “ImmunoTargets and Therapy” This study found that tumor immunotherapy, while effective against solid tumors, can disrupt the immune balance in hair follicles, causing follicular toxicity and alopecia, highlighting the need for targeted interventions to manage these adverse effects.
4 citations
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April 2010 in “Expert review of dermatology” This article discusses the immune privilege in hair follicles and suggests that restoring its collapse might be an effective strategy for treating alopecia areata and cicatricial alopecia, but it reports no new clinical results.
January 2016 in “Human & Experimental Toxicology” This study reported that CCT oligodeoxynucleotide induced patchy hair loss in male mice with specific genetic traits, suggesting gender and genetic preferences in immune response.
147 citations
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November 2020 in “International Journal of Molecular Sciences” This review discusses the immune roles of keratinocytes in wound healing and chronic wound inflammation, emphasizing their potential impact on chronic wound pathology and highlighting areas for future research.